Results 81 to 90 of about 9,336,586 (256)

Genome wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget’s disease of bone

Nature Genetics, 2010
Paget's disease of bone (PDB) is a common disorder with a strong genetic component characterized by focal increases in bone turnover, which in some cases is caused by mutations in SQSTM1. To identify additional susceptibility genes, we performed a genome-
O. Albagha, M. Visconti, N. Alonso, A. Langston, T. Cundy, R. Dargie, M. Dunlop, W. Fraser, M. Hooper, G. Isaia, G. Nicholson, J. del Pino Montes, R. González-Sarmiento, M. di Stefano, A. Tenesa, J. Walsh, S. Ralston   +16 more
semanticscholar   +1 more source

Single‐Center Epidemiological Analysis of Malignant Transformation With Skin Ulcers in Outpatients

International Wound Journal, Volume 23, Issue 1, January 2026.
ABSTRACT Investigate the epidemiological characteristics of outpatients initially diagnosed with skin ulcers who were ultimately confirmed to have cutaneous malignant tumours, and provide a diagnostic and therapeutic basis for the occurrence of secondary diseases in chronic wounds.
Yaoyao Kong, Haixia Wang, Nan Cao, Pengcheng Huai, Zhenzhen Wang, Chaoqi Zuo, Xueqing Wang, Yilei Wu, Yongxia Liu, Shengli Chen, Hong Liu, Guangliang Zhang   +11 more
wiley   +1 more source

Paget’s Disease of Maxilla with Paranasal Sinuses: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Paget’s disease of bone is a chronic skeletal disorder affecting predominantly elderly individuals. The pelvic girdle is the most common site to be affected; however, other sites such as long bones, spine, and skull are also frequently affected.
Amurtham Veeramani, Rr Mahendra Raj, Saravanan Thalaimalai, Abirami Moorthy, Preethi Paramasivam   +4 more
doaj   +1 more source

Perianal Paget's disease [PDF]

Journal of the Royal Society of Medicine, 1998
Perianal Paget's disease is rare. Unlike Paget's disease of the nipple, which is always associated with a subjacent breast adenocarcinoma, perianal Paget's disease is not always associated with a subjacent or visceral malignancy. The treatment recommendation in nearly all reported cases has been surgical excision.
openaire   +2 more sources

Metastatic Extramammary Paget's Disease of Scrotum Responds Completely to Single Agent Trastuzumab in a Hemodialysis Patient: Case Report, Molecular Profiling and Brief Review of the Literature

Case Reports in Oncological Medicine, 2015
Extramammary Paget's disease (EMPD) is a rare cancer. Although EMPD is usually noninvasive and treated with local therapy, once metastatic the prognosis of EMPD is poor and treatment options are limited.
P. Barth, Essel Dulaimi Al-Saleem, K. Edwards, S. Millis, Y. Wong, D. Geynisman   +5 more
semanticscholar   +1 more source

Extramammary Paget’s disease

BJR|case reports, 2016
The purpose of this report is to describe an unusual case of extramammary Paget's disease with urethral and lymph node infiltration and demonstrate the role of MRI in the pre-operative period for the assessment, management and prognosis of the disease.
Vasquez, Andres, Dominguez, Cristina, Rolon, Mariam   +2 more
openaire   +2 more sources

Epidemiology and pathology of Paget’s disease of bone – a review

Wiener Medizinische Wochenschrift, 2016
SummaryPaget’s disease of bone (PDB) is a noninflammatory, metabolic, skeletal disorder characterized by localized excessive osteoclastic bone resorption that is followed by compensatory increased osteoblastic activity leading to unstructured ...
E. Nebot Valenzuela, P. Pietschmann
semanticscholar   +1 more source

Perianal Paget's disease

Journal of Coloproctology, 2019
Paget's disease most commonly affects the breast. Extramammary involvement is rare, and the most commonly affected sites are the vulva, anus, perianal region, and axilla. The disease may progress to invasive adenocarcinoma or synchronous cancers.
Ornella Sari Cassol, Júlia Pastorello, Bruna de Oliveira, Lucas Henrique Lenhardt, Suéllen Montagna, Vanessa Locatelli Pietrobelli   +5 more
doaj   +1 more source

Paget's disease: a family with six cases. [PDF]

, 1967
James Jones, Michael F. Reed
openalex   +1 more source

Bilateral Paget’s Disease of the Breast—Case Report of Long-Time Misdiagnosed Tumors with Underlying Ductal Carcinomas and Review of the Literature

Case Reports in Dermatological Medicine, 2014
Paget’s disease of the breast is often misdiagnosed. We report on a 72-year old patient with a history of 2.5 years without any malignant findings, followed by the identification of a bilateral Paget’s disease with bilateral breast cancers.
Dietrich Barth
doaj   +1 more source