Results 131 to 140 of about 6,622 (149)
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Orthopedic Clinics of North America, 1990
Paget's disease of bone is defined as a process of increased bone remodeling; the primary event is increased resorption (osteoclastic activity) followed by subsequent reactive bone formation (osteoblastic activity). It is usually asymmetric and may be asymptomatic.
R L, Merkow, J M, Lane
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Paget's disease of bone is defined as a process of increased bone remodeling; the primary event is increased resorption (osteoclastic activity) followed by subsequent reactive bone formation (osteoblastic activity). It is usually asymmetric and may be asymptomatic.
R L, Merkow, J M, Lane
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Current Opinion in Endocrinology, Diabetes & Obesity, 2011
Abstract In 1876, Sir James Paget presented to the Royal Medical and Chirurgical Society of London an account of his experience with a previously unrecognized disease of the skeleton, which he termed osteitis deformans and has since born his name.
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Abstract In 1876, Sir James Paget presented to the Royal Medical and Chirurgical Society of London an account of his experience with a previously unrecognized disease of the skeleton, which he termed osteitis deformans and has since born his name.
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Trends in Endocrinology & Metabolism, 2008
Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result --a focal disorder of accelerated bone turnover--is easily recognized, the causes and evolution of the disorder remain uncertain.
Tim, Cundy, Mark, Bolland
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Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result --a focal disorder of accelerated bone turnover--is easily recognized, the causes and evolution of the disorder remain uncertain.
Tim, Cundy, Mark, Bolland
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Medical Journal of Australia, 2004
Paget's disease of bone is common, affecting up to 4% of Australians over the age of 55 years. The incidence of the disease and the severity of newly diagnosed cases appear to be falling, for unknown reasons. The cause of Paget's disease is unknown, but there is a strong genetic influence.
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Paget's disease of bone is common, affecting up to 4% of Australians over the age of 55 years. The incidence of the disease and the severity of newly diagnosed cases appear to be falling, for unknown reasons. The cause of Paget's disease is unknown, but there is a strong genetic influence.
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Best Practice & Research Clinical Rheumatology, 2003
Paget's disease of bone is characterized by an anarchic bone remodelling, associated with morphological and functional abnormalities of osteoclasts. Its prevalence and incidence rates decreased gradually over the past two decades; the reason for this remains unclear.
Mickaël, Rousière +3 more
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Paget's disease of bone is characterized by an anarchic bone remodelling, associated with morphological and functional abnormalities of osteoclasts. Its prevalence and incidence rates decreased gradually over the past two decades; the reason for this remains unclear.
Mickaël, Rousière +3 more
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Orthopedic Clinics of North America, 2015
The current understanding of Paget disease of bone (PDB) has vastly changed since Paget described the first case in 1877. Medical management of this condition remains the mainstay of treatment. Surgical intervention is usually only used in fractures through pagetic bone, need for realignment to correct deformity in major long bones, prophylactic ...
Mamun, Al-Rashid +5 more
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The current understanding of Paget disease of bone (PDB) has vastly changed since Paget described the first case in 1877. Medical management of this condition remains the mainstay of treatment. Surgical intervention is usually only used in fractures through pagetic bone, need for realignment to correct deformity in major long bones, prophylactic ...
Mamun, Al-Rashid +5 more
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Trends in Endocrinology & Metabolism, 1991
Paget's disease of bone is a common disorder of older patients that may sometimes cause a variety of signs and symptoms referable to the skeleton. An intrinsic bone-remodeling abnormality in this disease may lead to bone deformity, pain, and various arthritic or neurologic complications.
E S, Siris, R E, Canfield
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Paget's disease of bone is a common disorder of older patients that may sometimes cause a variety of signs and symptoms referable to the skeleton. An intrinsic bone-remodeling abnormality in this disease may lead to bone deformity, pain, and various arthritic or neurologic complications.
E S, Siris, R E, Canfield
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Seminars in Nuclear Medicine, 1976
Nuclear medicine techniques are currently playing an important complementary role in the evaluation, management, and follow-up of the patient who is suspected of having Paget's disease of bone. The earlier diagnoses made possible by some of the described techniques should lead to a better understanding of the basic pathophysiology and, in addition ...
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Nuclear medicine techniques are currently playing an important complementary role in the evaluation, management, and follow-up of the patient who is suspected of having Paget's disease of bone. The earlier diagnoses made possible by some of the described techniques should lead to a better understanding of the basic pathophysiology and, in addition ...
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Seminars in Musculoskeletal Radiology, 2016
Paget disease (PD) is a common disease of bone associated with abnormal bone turnover that in turn is due to an imbalance between osteoclastic and osteoblastic activity. There is good evidence that PD is reducing in incidence, prevalence, and severity.
Radhesh Krishna, Lalam +2 more
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Paget disease (PD) is a common disease of bone associated with abnormal bone turnover that in turn is due to an imbalance between osteoclastic and osteoblastic activity. There is good evidence that PD is reducing in incidence, prevalence, and severity.
Radhesh Krishna, Lalam +2 more
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The British Journal of Radiology, 1954
When I was invited by Professor Trueta to give a lecture I chose this subject because it is a condition which is recognisable by radiography long before the clinical evidence is distinctive and because I am able to demonstrate these earlier radiographic signs; though if you ask me what value I confer on the community by this early recognition I am less
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When I was invited by Professor Trueta to give a lecture I chose this subject because it is a condition which is recognisable by radiography long before the clinical evidence is distinctive and because I am able to demonstrate these earlier radiographic signs; though if you ask me what value I confer on the community by this early recognition I am less
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