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Mutant p62P392L Stimulation of Osteoclast Differentiation in Paget's Disease of Bone
, 2011 Kumaran Sundaram +3 more
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Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline. [PDF]
J Bone Miner Res, 2019 Ralston SH +16 more
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Bisphosphonates for Paget's disease of bone in adults. [PDF]
Cochrane Database Syst Rev, 2017 Corral-Gudino L +3 more
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Inflammatory cytokines in Paget's disease of bone
, 2013 Gláucio Ricardo Werner de Castro +3 more
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Calcified Tissue International, 2019
Paget's disease of bone (PDB) is a chronic and focal bone disorder, characterized by increased osteoclast-mediated bone resorption and a subsequent compensatory increase in bone formation, resulting in a disorganized mosaic of woven and lamellar bone at one or more affected skeletal sites.
Daniela Merlotti +4 more
openaire +6 more sources
Paget's disease of bone (PDB) is a chronic and focal bone disorder, characterized by increased osteoclast-mediated bone resorption and a subsequent compensatory increase in bone formation, resulting in a disorganized mosaic of woven and lamellar bone at one or more affected skeletal sites.
Daniela Merlotti +4 more
openaire +6 more sources
Medical Journal of Australia, 2004 Paget's disease of bone is common, affecting up to 4% of Australians over the age of 55 years. The incidence of the disease and the severity of newly diagnosed cases appear to be falling, for unknown reasons. The cause of Paget's disease is unknown, but there is a strong genetic influence.
David M. Reid, Kumar A. Vinod
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Orthopedic Clinics of North America, 1990
Paget's disease of bone is defined as a process of increased bone remodeling; the primary event is increased resorption (osteoclastic activity) followed by subsequent reactive bone formation (osteoblastic activity). It is usually asymmetric and may be asymptomatic.
Joseph M. Lane +2 more
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Paget's disease of bone is defined as a process of increased bone remodeling; the primary event is increased resorption (osteoclastic activity) followed by subsequent reactive bone formation (osteoblastic activity). It is usually asymmetric and may be asymptomatic.
Joseph M. Lane +2 more
openaire +3 more sources
Seminars in Musculoskeletal Radiology, 2002
Publisher Summary This chapter focuses on Paget's disease, which is a common disorder of the skeleton that is local in nature and extremely variable in its clinical manifestations. Skeletal deformity and pain are most common symptoms, and deformities are usually most apparent in the skull, face, and lower extremities.
Frederick R. Singer, G. David Roodman
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Publisher Summary This chapter focuses on Paget's disease, which is a common disorder of the skeleton that is local in nature and extremely variable in its clinical manifestations. Skeletal deformity and pain are most common symptoms, and deformities are usually most apparent in the skull, face, and lower extremities.
Frederick R. Singer, G. David Roodman
openaire +6 more sources