Results 231 to 240 of about 11,371 (266)
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Trends in Endocrinology & Metabolism, 2008
Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result --a focal disorder of accelerated bone turnover--is easily recognized, the causes and evolution of the disorder remain uncertain.
Mark J Bolland, Tim Cundy
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Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result --a focal disorder of accelerated bone turnover--is easily recognized, the causes and evolution of the disorder remain uncertain.
Mark J Bolland, Tim Cundy
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Best Practice & Research Clinical Rheumatology, 2003
Paget's disease of bone is characterized by an anarchic bone remodelling, associated with morphological and functional abnormalities of osteoclasts. Its prevalence and incidence rates decreased gradually over the past two decades; the reason for this remains unclear.
Mickaël Rousière +3 more
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Paget's disease of bone is characterized by an anarchic bone remodelling, associated with morphological and functional abnormalities of osteoclasts. Its prevalence and incidence rates decreased gradually over the past two decades; the reason for this remains unclear.
Mickaël Rousière +3 more
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Clinics in Geriatric Medicine, 1994
Paget's Disease of the bone is the second most common bone disease affecting the older population. Many of its symptoms are often erroneously attributed to the aging process. Its diagnosis is relatively simple. Means are now available to arrest the progress of the disease and restore a normal bone architecture.
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Paget's Disease of the bone is the second most common bone disease affecting the older population. Many of its symptoms are often erroneously attributed to the aging process. Its diagnosis is relatively simple. Means are now available to arrest the progress of the disease and restore a normal bone architecture.
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Clinical Biochemistry, 2012
To review recent advance in understanding the causation and management of Paget's disease.We review recent publications concerning the aetiology of the disease and the use of biochemical markers of bone turnover in diagnosis and treatment.Epidemiologic studies suggest that Paget's disease is decreasing in prevalence and severity (implying that ...
Tim Cundy, Ian R. Reid
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To review recent advance in understanding the causation and management of Paget's disease.We review recent publications concerning the aetiology of the disease and the use of biochemical markers of bone turnover in diagnosis and treatment.Epidemiologic studies suggest that Paget's disease is decreasing in prevalence and severity (implying that ...
Tim Cundy, Ian R. Reid
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Orthopedic Clinics of North America, 2015
The current understanding of Paget disease of bone (PDB) has vastly changed since Paget described the first case in 1877. Medical management of this condition remains the mainstay of treatment. Surgical intervention is usually only used in fractures through pagetic bone, need for realignment to correct deformity in major long bones, prophylactic ...
Mamun Al-Rashid +6 more
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The current understanding of Paget disease of bone (PDB) has vastly changed since Paget described the first case in 1877. Medical management of this condition remains the mainstay of treatment. Surgical intervention is usually only used in fractures through pagetic bone, need for realignment to correct deformity in major long bones, prophylactic ...
Mamun Al-Rashid +6 more
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Trends in Endocrinology & Metabolism, 1991
Paget's disease of bone is a common disorder of older patients that may sometimes cause a variety of signs and symptoms referable to the skeleton. An intrinsic bone-remodeling abnormality in this disease may lead to bone deformity, pain, and various arthritic or neurologic complications.
Ethel S. Siris, Robert E. Canfield
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Paget's disease of bone is a common disorder of older patients that may sometimes cause a variety of signs and symptoms referable to the skeleton. An intrinsic bone-remodeling abnormality in this disease may lead to bone deformity, pain, and various arthritic or neurologic complications.
Ethel S. Siris, Robert E. Canfield
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Seminars in Musculoskeletal Radiology, 2016
Paget disease (PD) is a common disease of bone associated with abnormal bone turnover that in turn is due to an imbalance between osteoclastic and osteoblastic activity. There is good evidence that PD is reducing in incidence, prevalence, and severity.
Radhesh Lalam +2 more
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Paget disease (PD) is a common disease of bone associated with abnormal bone turnover that in turn is due to an imbalance between osteoclastic and osteoblastic activity. There is good evidence that PD is reducing in incidence, prevalence, and severity.
Radhesh Lalam +2 more
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2011
In 1876, Sir James Paget presented to the Royal Medical and Chirurgical Society of London an account of his experience with a previously unrecognized disease of the skeleton, which he termed osteitis deformans and has since born his name. Paget’s disease of bone is a focal skeletal disorder which progresses slowly and leads to changes in the shape and ...
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In 1876, Sir James Paget presented to the Royal Medical and Chirurgical Society of London an account of his experience with a previously unrecognized disease of the skeleton, which he termed osteitis deformans and has since born his name. Paget’s disease of bone is a focal skeletal disorder which progresses slowly and leads to changes in the shape and ...
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Seminars in Nuclear Medicine, 1976
Nuclear medicine techniques are currently playing an important complementary role in the evaluation, management, and follow-up of the patient who is suspected of having Paget's disease of bone. The earlier diagnoses made possible by some of the described techniques should lead to a better understanding of the basic pathophysiology and, in addition ...
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Nuclear medicine techniques are currently playing an important complementary role in the evaluation, management, and follow-up of the patient who is suspected of having Paget's disease of bone. The earlier diagnoses made possible by some of the described techniques should lead to a better understanding of the basic pathophysiology and, in addition ...
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The British Journal of Radiology, 1954
When I was invited by Professor Trueta to give a lecture I chose this subject because it is a condition which is recognisable by radiography long before the clinical evidence is distinctive and because I am able to demonstrate these earlier radiographic signs; though if you ask me what value I confer on the community by this early recognition I am less
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When I was invited by Professor Trueta to give a lecture I chose this subject because it is a condition which is recognisable by radiography long before the clinical evidence is distinctive and because I am able to demonstrate these earlier radiographic signs; though if you ask me what value I confer on the community by this early recognition I am less
openaire +3 more sources