Results 81 to 90 of about 9,984 (217)

Proteomic Signatures Over Age Reveal Significant Changes From Infancy Till Late Adulthood

Advanced Biology, Volume 10, Issue 1, January 2026.
Age‐specific changes in the serum proteome were investigated across the entire lifespan, from infancy till late adulthood by analyzing 178 proteins in serum samples of healthy individuals. Using various analyses approaches, distinct protein expression profiles and four protein patterns during aging were identified.
Eveline M. Delemarre, Hidde M. Smits, Debbie van Baarle, Marlies A. van Houten, Fiona R. M. van der Klis, Helen L. Leavis, Joel A. G. van Roon, Lilly M. Verhagen, Joanne G. Wildenbeest, Femke van Wijk, Julia Drylewicz, Stefan Nierkens   +11 more
wiley   +1 more source

Fibrohistiocitoma maligno óseo tras degeneración de enfermedad de Paget Caso clínico y revisión de la literatura [PDF]

, 1996
El fibrohistiocitoma maligno óseo es un tumor de estirpe mesenquimal poco frecuente, pero de alta agresividad. Se suele presentar de forma primaria, aunque a veces lo hace sobre lesiones previas en el hueso.
Candel García, L., Cecilia López, David, Delgado Díaz, E., Olaguibel Álvarez-Valdés, R., Zafra Jimenez, J. A.   +4 more
core  

Alendronate induces anti-migratory effects and inhibition of neutral phosphatases in UMR106 osteosarcoma cells [PDF]

, 2007
Bisphosphonates are nonhydrolysable pyrophosphate analogues that prevent bone loss in several types of cancer. However, the mechanisms of anticancer action of bisphosphonates are not completely known.
Bruzzone, L., Cortizo, Ana María, Molinuevo, M.S.   +2 more
core   +2 more sources

Paget's Disease of Bone [PDF]

Journal of Bone and Mineral Research, 1998
Abstract Paget's disease of bone is a localized disorder of bone remodeling. Increased numbers of larger than normal osteoclasts initiate the process at affected skeletal sites, and the increase in bone resorption is followed by an increase in new bone formation, altering bone architecture.
openaire   +2 more sources

TREATMENT OF PAGET'S DISEASE OF BONE [PDF]

Clinical Endocrinology, 1988
There are two major types of agent available to suppress disease activity: calcitonin, and the bisphosphonates (formerly called diphosphonates). Other agents, including fluoride, mithramycin, actinomycin-D, glucocorticoids, colchicine, glucagon and inosiplex, have also been investigated, but are either ineffective, toxic or ...
D, Anderson, J C, Cantrill
openaire   +3 more sources

Management of Cervical Root Resorption on the Palatal Aspect Using Combined Internal and External Surgical Approaches: A Case Report Study

Case Reports in Dentistry, Volume 2026, Issue 1, 2026.
External cervical resorption (ECR) is a progressive disease that occurs at the cervical region of the tooth, developing beneath the epithelial attachment. ECR is often asymptomatic and detected in routine radiographic examinations. This condition can significantly impact the long‐term survival of the affected tooth.
Sahar Shafagh, Marjan Bolbolian, Mahsa Zohdi, Kevin Seymour   +3 more
wiley   +1 more source

Prophylactic zoledronic acid therapy to prevent or modify Paget’s disease of bone progression in adults with SQSTM1 mutations: the ZiPP RCT

Efficacy and Mechanism Evaluation
Background Paget’s disease of bone is characterised by focal abnormalities of bone turnover resulting in various complications. It often presents at an advanced stage with irreversible bone damage. At this point, the symptomatic benefits of treatment are
Jonathan Phillips, Deepak Subedi, Steff C Lewis, Catriona Keerie, Stuart H Ralston   +4 more
doaj   +1 more source

Evaluation of Cell‐Extracellular Vesicle Interaction Using a Microfluidic Microsystem (CellExoChip)

Advanced Materials Technologies, Volume 10, Issue 23, December 3, 2025.
A new microfluidic platform, the CellExoChip, reveals how cancer cells interact with exosomes to influence metastasis. This device isolates cancer cells and tracks their uptake exosomes and secretion of their exosomes in response to other exosomes. Lung cancer cells are showed preferentially absorb and respond to their own exosomes—hinting at a hidden ...
Nna‐Emeka Onukwugha, Zeqi Niu, Abha Kumari, Scott Smith, Grace Li, Kruthi Srinivasa Raju, Joseph Marvar, Thomas Leekley, Shawn Fortna, Yoon‐Tae Kang, Sunitha Nagrath   +10 more
wiley   +1 more source

Pseudoartrosis de húmero en la enfermedad de Paget: presentación de un caso [PDF]

, 1997
Presentamos un paciente diagnosticado de enfermedad de Paget que sufrió una fractura patológica del húmero. El tratamiento ortopédico de la fractura deparó una pseudoartrosis. El resultado del tratamiento quirúrgico de ésta fue bueno.
González Orús, A., Mencía Barrio, Ricardo, Ramos Pascua, Luis R., Santos, J.Á.   +3 more
core  

Considerações sobre os marcadores bioquímicos do metabolismo ósseo e sua utilidade prática [PDF]

, 1999
The use of biochemical markers of bone turnover in clinical practice is an ever increasing field. The development of new methods and a better knowledge of the physiopathology of the bone diseases, mainly osteoporosis, are the main reason for that.
Vieira, José Gilberto H [UNIFESP]
core   +3 more sources