First Case of Primary Breast Melanoma in Central America: Case Report and Literature Review
Clinical Case Reports, Volume 13, Issue 12, December 2025.ABSTRACT Primary breast melanoma is an exceedingly rare neoplasm, accounting for < 0.5% of all malignant breast tumors. Its scarcity and highly variable clinical presentation often delay diagnosis and complicate management. We report the case of a 55‐year‐old woman with a primary non‐cutaneous melanoma of the right breast initially misdiagnosed as high‐
Ana García‐Urbina +3 more
wiley +1 more source
Pachydermoperiostosis-Like Disease In Captive Red Ruffled Lemurs (Varecia Variegatus Rubra) [PDF]
, 2011 Pachydermatoperiostosis, a rare form of hypertrophic osteoarthropathy, is of unknown etiology and previously thought limited to humans. The only periosteal reaction previously reported in prosimians is related to renal disease.
Bruce Rothschild +2 more
core +1 more source
Genetic modifiers of cognitive maintenance among older adults. [PDF]
, 2014 ObjectiveIdentify genetic factors associated with cognitive maintenance in late life and assess their association with gray matter (GM) volume in brain networks affected in aging.MethodsWe conducted a genome-wide association study of ∼2.4 M markers to ...
Coppola, Giovanni +5 more
core +1 more source
A case of mandible Paget’s disease of the bone treated with intravenous neridronate
Reumatismo, 2016 Paget’s disease of bone (PDB) is a focal disorder of osteoclasts, leading to chaotic bone remodelling, and it is characterized by the presence of focal areas of excessive bone formation alongside with areas of focal bone resorption.
A. Fassio +4 more
doaj +1 more source
Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-beta and Runx2 in bone is required for hearing [PDF]
, 2010 Publisher version: http://www.nature.com/embor/journal/v11/n10/full/embor2010135.htmlDA - 20100917 IS - 1469-3178 (Electronic) IS - 1469-221X (Linking) LA - ENG PT - JOURNAL ARTICLEDA - 20100917 IS - 1469-3178 (Electronic) IS - 1469-221X (Linking) LA ...
Alexandra E Porter +21 more
core +1 more source
Primary lymphoma arising in Paget’s disease in a patient with primary hyperparathyroidism
European Journal of Case Reports in Internal MedicineBackground: Paget’s disease of bone (PDB) is characterized by a disturbance of the balance between bone formation and bone resorption at one or more bone sites.
Mercedes De La Fuente +5 more
doaj +1 more source
Paget's disease (osteitis deformans) [PDF]
, 2009 This issue of eMedRef provides information to clinicians on the pathophysiology, diagnosis, and therapeutics of Paget's ...
Bryce, Brandon
core
Monostotic osteitis deformans of lumbar vertebra: A rare phenomenon in Eastern Asia
Journal of Medical Sciences, 2017 Osteitis deformans, also known as Paget's disease, is characterized by accelerated osteoclastic activity followed by ineffective osteoblastic activity resulting in a deformed and fragile bone. It is more prevalent in Western Europe and relatively rare in
Arun-Kumar Kaliya-Perumal +3 more
doaj +1 more source
ORGAN SPECIFIC VASCULAR RESPONSE TO FIBROSIS AFFECTS BREAST CANCER METASTATIC ORGANOTROPISM [PDF]
, 2016 The solid tumor microenvironment, pre-metastatic niche, and fibrotic environment are known to have significant biochemical and biomechanical similarities to the fibrotic environment. All have significantly increased levels of factors such as TGFβ, HIF1α,
Fletcher, Eliot S, Fletcher, Eliot S
core +1 more source
Evaluation of mental health using MHC-SF in patients with paget’s bone disease
European PsychiatryIntroduction Paget’s disease is a chronic bone disorder, that is characterized by increased and disorganized bone remodelling, which can lead to bone pain, bone complications such as deformities and fractures, neurological and cardiovascular ...
A. Feki +10 more
doaj +1 more source