Results 81 to 90 of about 174,879,615 (167)
The influence of pyridyl and imidazole substituents on the biological properties of alendronate derivatives is investigated. A series of heterocyclic N‐substituted bisphosphonates is synthesized and evaluated for hydroxyapatite binding and antiproliferative activity.
Anna Nasulewicz‐Goldeman +3 more
wiley +1 more source
Cancer‐Related Fever in Metastatic Prostate Cancer: A Case Report
ABSTRACT Fever in cancer patients is often mistakenly attributed to infection, leading to unnecessary antibiotic use. Neoplastic fever, though well‐documented in hematologic malignancies, is rare in solid tumors, particularly prostate cancer. This case report presents an 81‐year‐old male with metastatic prostate cancer, who was admitted to Razi ...
Masoud Maboudi +3 more
wiley +1 more source
Treatment of Paget’s Disease of Bone
Paget's disease involves overactivity of both osteoblasts and osteoclasts within affected bone tissue. It is unclear in which cells the causative lesion resides, but therapies have generally been antiosteoclastic (antiresorptive) because these are the ...
Ian R. Reid, Reid, IR
core +1 more source
Paget's disease of bone: A rare case report
Paget's disease of bone (PDB) is a localized bone remodeling disorder that is chronic, non-inflammatory.. It is also known as “osteodystrophia deformans” as described by Sir James Paget. PDB is the second most common bone disease after osteoporosis. This
Mohsin M Tak +2 more
doaj +1 more source
ABSTRACT Gallbladder carcinoma is an aggressive malignancy often diagnosed at an advanced stage. Skeletal metastasis, especially mixed lytic‐sclerotic lesions, is rare and typically occurs late. This report highlights an unusual presentation where widespread bony metastases were the initial manifestation, leading to the diagnosis of gallbladder ...
Shivali Rao +2 more
wiley +1 more source
[english] We report on a 42-year-old woman who presented with persistent pain in her left knee with no history of trauma. Sagittal T1-weighted MRI of the left knee showed discontinuity between the anterior and posterior horns of the left medial meniscus,
Ganger, Rudolf +9 more
core +1 more source
Clinical efficacy and safety of zoledronic acid in osteoporosis and Paget's disease [PDF]
Osteoporosis and Paget’s bone disease are the most common diseases of the bone. In addition to glucocorticoid treatment, there are many other secondary causes of osteoporosis. Bisphosphonates are used to treat these bone conditions.
Doggrell, Sheila, Sheila A Doggrell
core +1 more source
PAGET'S DISEASE: CURRENT TREATMENT MODALITIES
Paget's disease is a chronic local bone disease included into a group of metabolic osteopathies in which rearrangement foci emerge in one or several bones.
Yulia Leonidovna Korsakova
doaj +1 more source
ABSTRACT Background Frailty and osteoporosis are interrelated conditions that predominantly affect older adults. The greater the individual's frailty, the greater the probability of suffering a fracture and the greater the risk of fractures occurring in the future. Therefore, this study aimed to verify whether anti‐fracture pharmacological therapies in
Anna Julia Lacerda Raposo Freire +3 more
wiley +1 more source
Bisphosphonates are widely used to treat osteoporosis and to manage bone metastases in patients with breast cancer. Nitrogen‐based bisphosphonates may also broadly reduce cancer risk, but evidence remains inconsistent. This large population‐based data linkage study in women aged > 50 years found that, compared to no use of osteoporosis medicines ...
Karen M. Tuesley +7 more
wiley +1 more source

