Results 81 to 90 of about 174,879,615 (167)

Synthesis of a Series of Heterocyclic N‐Substituted Derivatives of Alendronic Acid and Their Preliminary Biological Evaluation

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
The influence of pyridyl and imidazole substituents on the biological properties of alendronate derivatives is investigated. A series of heterocyclic N‐substituted bisphosphonates is synthesized and evaluated for hydroxyapatite binding and antiproliferative activity.
Anna Nasulewicz‐Goldeman   +3 more
wiley   +1 more source

Cancer‐Related Fever in Metastatic Prostate Cancer: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Fever in cancer patients is often mistakenly attributed to infection, leading to unnecessary antibiotic use. Neoplastic fever, though well‐documented in hematologic malignancies, is rare in solid tumors, particularly prostate cancer. This case report presents an 81‐year‐old male with metastatic prostate cancer, who was admitted to Razi ...
Masoud Maboudi   +3 more
wiley   +1 more source

Treatment of Paget’s Disease of Bone

open access: yes, 2016
Paget's disease involves overactivity of both osteoblasts and osteoclasts within affected bone tissue. It is unclear in which cells the causative lesion resides, but therapies have generally been antiosteoclastic (antiresorptive) because these are the ...
Ian R. Reid, Reid, IR
core   +1 more source

Paget's disease of bone: A rare case report

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2020
Paget's disease of bone (PDB) is a localized bone remodeling disorder that is chronic, non-inflammatory.. It is also known as “osteodystrophia deformans” as described by Sir James Paget. PDB is the second most common bone disease after osteoporosis. This
Mohsin M Tak   +2 more
doaj   +1 more source

Disseminated Mixed Lytic‐Sclerotic Skeletal Metastases as Initial Presentation of Gallbladder Carcinoma: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Gallbladder carcinoma is an aggressive malignancy often diagnosed at an advanced stage. Skeletal metastasis, especially mixed lytic‐sclerotic lesions, is rare and typically occurs late. This report highlights an unusual presentation where widespread bony metastases were the initial manifestation, leading to the diagnosis of gallbladder ...
Shivali Rao   +2 more
wiley   +1 more source

Varus deformity of the left lower extremity causing degenerative lesion of the posterior horn of the left medial meniscus in a patient with Paget’s disease of bone

open access: yes, 2014
[english] We report on a 42-year-old woman who presented with persistent pain in her left knee with no history of trauma. Sagittal T1-weighted MRI of the left knee showed discontinuity between the anterior and posterior horns of the left medial meniscus,
Ganger, Rudolf   +9 more
core   +1 more source

Clinical efficacy and safety of zoledronic acid in osteoporosis and Paget's disease [PDF]

open access: yes, 2009
Osteoporosis and Paget’s bone disease are the most common diseases of the bone. In addition to glucocorticoid treatment, there are many other secondary causes of osteoporosis. Bisphosphonates are used to treat these bone conditions.
Doggrell, Sheila, Sheila A Doggrell
core   +1 more source

PAGET'S DISEASE: CURRENT TREATMENT MODALITIES

open access: yesСовременная ревматология, 2010
Paget's disease is a chronic local bone disease included into a group of metabolic osteopathies in which rearrangement foci emerge in one or several bones.
Yulia Leonidovna Korsakova
doaj   +1 more source

Effectiveness and Safety of Pharmacological Therapy for Osteoporosis in Frail Elderly Individuals: Systematic Review and Meta‐Analysis

open access: yesHealth Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Frailty and osteoporosis are interrelated conditions that predominantly affect older adults. The greater the individual's frailty, the greater the probability of suffering a fracture and the greater the risk of fractures occurring in the future. Therefore, this study aimed to verify whether anti‐fracture pharmacological therapies in
Anna Julia Lacerda Raposo Freire   +3 more
wiley   +1 more source

Nitrogen‐Based Bisphosphonate Use and Risk of Cancer in Women Aged 50 Years and Older: A National Data Linkage Study

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1669-1685, 1 October 2026.
Bisphosphonates are widely used to treat osteoporosis and to manage bone metastases in patients with breast cancer. Nitrogen‐based bisphosphonates may also broadly reduce cancer risk, but evidence remains inconsistent. This large population‐based data linkage study in women aged > 50 years found that, compared to no use of osteoporosis medicines ...
Karen M. Tuesley   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy