Results 61 to 70 of about 166,331,074 (168)
Bisphosphonates are widely used to treat osteoporosis and to manage bone metastases in patients with breast cancer. Nitrogen‐based bisphosphonates may also broadly reduce cancer risk, but evidence remains inconsistent. This large population‐based data linkage study in women aged > 50 years found that, compared to no use of osteoporosis medicines ...
Karen M. Tuesley +7 more
wiley +1 more source
Paget’s disease of bone (PDB) affects up to 1% of people of European origin aged 55 years and above. It is characterized by focal abnormalities of bone remodelling which disrupt normal bone architecture, leading to expansion and reduced mechanical ...
Stuart H. Ralston
core +1 more source
Objective This retrospective cohort study evaluated the long‐term discontinuation (LTD) of osteoporosis treatments in postmenopausal women in France and associated fracture risk and economic burden. Methods From the national French health care database (Système National des Données de Santé), we included postmenopausal women aged ≥60 years initiating ...
Audrey Lajoinie +6 more
wiley +1 more source
Digital Implant Rehabilitation in Multiple Idiopathic Root Resorption: A Case Report
ABSTRACT Multiple idiopathic root resorptions (MIRs) represent a rare condition with uncertain etiology and limited treatment options, and they may compromise the prognosis of affected teeth. A digitally guided interdisciplinary approach combining cone‐beam computed tomography (CBCT) diagnostics, virtual implant planning, and immediate implant ...
Shoresh Afnan +3 more
wiley +1 more source
Incidence of Paget’s Disease of Bone in the UK: Evidence of a Continuing Decline [PDF]
Objectives: To characterise the incidence of clinically diagnosed Paget’s disease of bone in the UK during 1999-2015 and to determine variation in incidence of disease by age, sex, geography and level of deprivation.Methods: Incident cases of Paget’s ...
Ashcroft, Darren; id_orcid +5 more
core +1 more source
Genetic Determinants of Treatment‐Related Bone Toxicity in Pediatric Acute Lymphoblastic Leukemia
Osteonecrosis and fractures are serious corticosteroid‐induced bone toxicities in children treated for acute lymphoblastic leukemia, yet their genetic determinants remain incompletely defined. In this study, we aimed to identify novel genetic contributors to bone toxicity and to evaluate the robustness of both newly identified and previously ...
Rachid Abaji +14 more
wiley +1 more source
DIAGNOSTIC ASPECTS OF PAGET’S DISEASE OF BONE IN CLINICAL PRACTICE [PDF]
Paget’s disease of bone (PDB) is a chronic localized skeletal disease that belongs to a group of metabolic osteopathies and is characterized by impaired bone remodeling to form foci of increased bone resorption followed by replacement with an excessive ...
N. S. Nikolaev +3 more
core +1 more source
MicroRNAs expression profiling in Paget’s Disease of Bone, Osteoporosis and Hyperparathyroidism [PDF]
Excluding monogenic bone disorders, it is now well established that in complex multifactorial diseases, with a recognized hereditary component, such as Paget’s disease of bone and osteoporosis, the associated genetic variants have a limited impact on ...
Bianciardi Simone
core +1 more source
Sodium Intake and Osteoporosis Risk: Evidence From NHANES and Mendelian Randomization Analysis
This study combined cross‐sectional data from the National Health and Nutrition Examination Survey (NHANES) with Mendelian Randomization (MR) analysis to systematically investigate the relationship between sodium intake and osteoporosis. The results showed that within a specific intake range (> 6150 mg/day), sodium intake was significantly negatively ...
Yunxiao Ji +5 more
wiley +1 more source
Determinants of quality of life in Paget's disease of bone
Objective: To evaluate the parameters associated with quality of life in patients with Paget's disease of bone. Methods: Patients with Paget's disease of bone were evaluated with SF-36 and WHOQOL-bref questionnaires.
Gláucio Ricardo Werner de Castro +10 more
doaj +1 more source

