Results 1 to 10 of about 166,331,801 (189)
Paget's disease of bone in the patient presented with a bowed leg [PDF]
Key Clinical Message In dealing with bowed limbs along with increased alkaline phosphatase (ALP), even if the typical changes to the face are not very noticeable at first glance, Paget's disease of the bone (PDB) should be suspected, and the necessary ...
Mehrzad Hajialiloo +1 more
doaj +2 more sources
Updates on Paget’s Disease of Bone [PDF]
Paget’s disease of the bone is a prevalent bone disease characterized by disorganized bone remodeling; however, it is comparatively uncommon in East Asian countries, including China, Japan, and Korea. The exact cause still remains unknown. In genetically
Yong Jun Choi +2 more
doaj +2 more sources
Paget's disease of bone in Tunisia: A study of 69 patients [PDF]
Context: Paget's disease of bone is a common bone disease with a striking variation in its incidence and characteristics in different parts of the world. It is uncommonly reported in African patients.
Kaouther Maatallah +8 more
doaj +2 more sources
Radiological impact of oral bisphosphonate use on polyostotic Paget's disease of bone over a 2 year period [PDF]
Paget's disease of bone is a disorder of osteoclasts which hampers the physiological process of bone remodeling. It is the most common metabolic orthopedic disease in the Caucasian populace; we report the diagnosis of Paget's disease of bone in a South ...
Christopher Jude Pinto, MD +3 more
doaj +2 more sources
Paget’s Disease of Bone and Normocalcemic Variant of Primary Hyperparathyroidism in an Osteoporotic Male: Exceptional Coexistence [PDF]
Background and clinical significance: Paget’s disease of bone involves anomalies of the bone metabolism; however, the presence of tumor-derivate abnormal parathyroid hormone (PTH) levels does not represent one of these disturbances. To our best knowledge,
Ana-Maria Gheorghe +4 more
doaj +2 more sources
Paget’s disease of bone: pathogenesis, ocular manifestations, and therapeutic strategies [PDF]
Objective Paget’s disease of bone (PDB) is a chronic, focal metabolic bone disorder characterized by increased bone destruction and disordered bone formation, and is a rare disease in Asian populations.
Bei Li, Yifan Kang
doaj +2 more sources
Role of Denosumab in Chronic Kidney Disease with Paget’s Disease of Bone: A Case Report and Review of Literature [PDF]
Introduction: Paget’s disease of bone (PDB) is rarely encountered in patients with chronic kidney disease (CKD), with limited reports in the literature. The coexistence of these conditions poses significant diagnostic and therapeutic challenges.
Manjunath Totaganti +5 more
doaj +2 more sources
Paget's Disease of the Bone [PDF]
Paget's disease of bone (PDB) is a localised disorder of bone remodelling, characterised by enhanced resorption of bone by giant multinucleated osteoclasis followed by formation of disorganised woven bone by osteoblasts. The resultant bone is expanded, weak and vascular, causing bone pain brittleness and deformity.
K, Narayanan +2 more
openaire +4 more sources
SummaryPaget's disease of bone is a relatively common condition in the UK affecting up to 5% of the population over the age of 55 years with particularly high prevalence in the North West of England. The majority of those affected are asymptomatic. Its precise cause remains unknown, and until recently, choice of treatment of this sometimes painful and ...
C G, Ooi, W D, Fraser
+8 more sources
Paget’s disease of bone is a focal disorder of unknown etiology characterized initially by excessive resorption and subsequently by excessive formation of bone, culminating in a “mosaic” pattern of lamellar bone associated with extensive local vascularity and increased fibrous tissue in adjacent marrow.
+8 more sources

