Results 21 to 30 of about 166,331,801 (189)
QJM, 2014 Paget's disease is an osteoclastic-mediated disorder of bone that results in abnormal bone resorption associated with inadequate remodeling that leads to mechanically weakened bone. Demonstrating variable geographic prevalence, it is becoming less frequent and age of onset is lengthening in areas of once high prevalence prior to the institution of ...
Gregory, Gruener, Pauline, Camacho
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The Journal of Bone and Joint Surgery. British volume, 1979 This chapter focuses on Paget's disease of bone. The pathological hallmark of the Paget's bone disease is excessive and disorganized activity of bone that involves both matrix and mineral. There is no idea of its cause and little knowledge of its natural history; however, the biochemical changes produced by the overactive bone justify its inclusion as ...
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Journal of Orthopaedic Surgery and Research, 2010 Paget's disease of the bone is a common metabolic bone disease in most European countries, Australia, New Zealand, and North America. Conversely, this disease is rare in Scandinavia, Asia, and Africa.
Fukuta Masashi +4 more
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Pathobiology of Paget’s Disease of Bone [PDF]
, 2014 Paget's disease of bone is characterized by highly localized areas of increased bone resorption accompanied by exuberant, but aberrant new bone formation with the primary cellular abnormality in osteoclasts. Paget's disease provides an important paradigm
Galson, Deborah L., Roodman, G. David
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Tumor-Associated Hypercalcemia in a Patient with Paget's Disease
Kaohsiung Journal of Medical Sciences, 2008 Paget's disease of the bone, which is characterized by a focal region of highly exaggerated bone remodeling, is very rare in Asia. Most patients with Paget's disease are asymptomatic; they are normocalcemic and show elevated alkaline phosphatase levels ...
Hao-Chang Hung +4 more
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Isolated Paget’s Disease of Frontal Bone: A Case Report
Endocrinology Research and Practice, 2022 There are several reports about Paget’s disease. We report a case who presented with headache and found to be have isolated Paget’s disease of frontal bone with normal serum alkaline phosphatase which was not reported previously.
Esin Eray +2 more
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Paget's Disease: Skeletal Manifestations and Effect of Bisphosphonates [PDF]
, 2017 BACKGROUND: Paget's disease of bone leads to change in the shape and size of the bone and results in reduced bone strength, leading to the complications of deformity, arthritis, and fracture.
양규현, 강호, 박영창
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BMJ, 1981 The essential requirement for effective treatment of Paget’s disease of bone is that the characteristic abnormality of bone remodelling is predictably corrected without the occurrence of significant side effects. Although the ideal agent is not currently available, appropriate use of the calcitonins or diphosphonates goes a long way to achieving this ...
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Paget’s disease of bone: A rare case in a patient under 40 years of age
Human Pathology Reports, 2021 Paget’s disease of bone is a rare diagnosis in patients under 40 years of age. We report a case diagnosed in a 35-year-old patient with suspected symptomatic presentation at the age of 30 years during pregnancy.
Erina Melva McKinney +4 more
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Journal of Medical Case Reports, 2010 Introduction Paget's disease of the bone is characterized by focal abnormalities of increased bone turnover affecting one or more sites throughout the skeleton.
Wada Takuro +3 more
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