Results 81 to 90 of about 11,714 (178)

Mechanical Competence and Bone Quality Develop During Skeletal Growth. [PDF]

, 2019
Bone fracture risk is influenced by bone quality, which encompasses bone's composition as well as its multiscale organization and architecture. Aging and disease deteriorate bone quality, leading to reduced mechanical properties and higher fracture ...
Amling, Michael, Busse, Björn, Chushkin, Yuriy, Gludovatz, Bernd, Püschel, Klaus, Riedel, Christoph, Ritchie, Robert O, Schaible, Eric, Schmidt, Felix N, Stockhausen, Kilian E, Vettorazzi, Eik, Zimmermann, Elizabeth A, Zontone, Federico   +12 more
core   +1 more source

Management of Cervical Root Resorption on the Palatal Aspect Using Combined Internal and External Surgical Approaches: A Case Report Study

Case Reports in Dentistry, Volume 2026, Issue 1, 2026.
External cervical resorption (ECR) is a progressive disease that occurs at the cervical region of the tooth, developing beneath the epithelial attachment. ECR is often asymptomatic and detected in routine radiographic examinations. This condition can significantly impact the long‐term survival of the affected tooth.
Sahar Shafagh, Marjan Bolbolian, Mahsa Zohdi, Kevin Seymour   +3 more
wiley   +1 more source

Genetic aspects of Paget’s disease of bone [PDF]

, 2004
Paget’s disease of bone (PDB) is a metabolic bone disease characterized by excessive bone resorption and formation due to increased osteoclasts activity.
Brandi, Maria Luisa, Falchetti, Alberto, Marini, Francesca, Masi, Laura   +3 more
core  

Uncoupling of p97 ATPase activity has a dominant negative effect on protein extraction [PDF]

, 2019
p97 is a highly abundant, homohexameric AAA+ ATPase that performs a variety of essential cellular functions. Characterized as a ubiquitin-selective chaperone, p97 recognizes proteins conjugated to K48-linked polyubiquitin chains and promotes their ...
Long, David T., Rycenga, Halley B., Wolfe, Kelly B., Yeh, Elizabeth S.   +3 more
core   +1 more source

Evaluation of Cell‐Extracellular Vesicle Interaction Using a Microfluidic Microsystem (CellExoChip)

Advanced Materials Technologies, Volume 10, Issue 23, December 3, 2025.
A new microfluidic platform, the CellExoChip, reveals how cancer cells interact with exosomes to influence metastasis. This device isolates cancer cells and tracks their uptake exosomes and secretion of their exosomes in response to other exosomes. Lung cancer cells are showed preferentially absorb and respond to their own exosomes—hinting at a hidden ...
Nna‐Emeka Onukwugha, Zeqi Niu, Abha Kumari, Scott Smith, Grace Li, Kruthi Srinivasa Raju, Joseph Marvar, Thomas Leekley, Shawn Fortna, Yoon‐Tae Kang, Sunitha Nagrath   +10 more
wiley   +1 more source

Florid cemento-osseous dysplasia: report of a case documented with clinical,radiographic, biochemical and histological findings [PDF]

, 2013
Florid cemento-osseous dysplasia (FCOD) has been described as a condition that characteristically affects the jaws of middle-aged black women. This condition has also been classified as gigantiform cementoma, chronic sclerosing osteomyelitis, sclerosing ...
Baris, Emre, Bozkaya, Süleyman, Ergün, Gülfem, Kutluay Köklü, Harika, Çankal, Dilek Aynur   +4 more
core   +1 more source

Further Evidence That Chondrocalcinosis 1 (CCAL1) is a Confirmed Mendelian Phenotype With a Known Molecular Basis

American Journal of Medical Genetics Part A, Volume 197, Issue 12, December 2025.
ABSTRACT Chondrocalcinosis (CCAL), also known as calcium pyrophosphate dihydrate deposition disease (CPPDD), is a frequent multifactorial condition in the elderly, but there are two rare autosomal dominant Mendelian forms, CCAL1 (OMIM %600668) and CCAL2. Only three families with molecularly proven CCAL1 have been reported.
Anna‐Christina Pansa, Mareike Selig, Markus Wingendorf, Matthew A. Brown, Oliver Bartsch   +4 more
wiley   +1 more source

p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein-Protein Interactions. [PDF]

, 2016
The AAA+ ATPase p97/VCP adopts at least three conformations that depend on the binding of ADP and ATP and alter the orientation of the N-terminal protein-protein interaction (PPI) domain into up and down conformations.
Arkin, Michelle, Bulfer, Stacie, Chou, Tsui-Fen   +2 more
core  

Boning up on autophagy: the role of autophagy in skeletal biology. [PDF]

, 2013
From an evolutionary perspective, the major function of bone is to provide stable sites for muscle attachment and affording protection of vital organs, especially the heart and lungs (ribs) and spinal cord (vertebrae and intervertebral discs).
Layfield, Robert, Lotz, Martin, Settembre, Carmine, Shapiro, Irving, Whitehouse, Caroline   +4 more
core   +2 more sources

A Case Report of Short‐Term Metastasis After Surgery for Mammary Paget's Disease

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Mammary Paget's disease (MPD) with ductal carcinoma in situ (DCIS) pathology can metastasize rapidly. HER2‐positive status likely drives aggression, warranting early postoperative systemic imaging and close surveillance. Anti‐HER2 agents require proactive toxicity management.
Chao Wang, Baiyi Yan, Jing Wang, Jiahui Zhou, Dongxu Li, Xiaofang Gao, Yong Pan   +6 more
wiley   +1 more source