Invasive acantholytic anaplastic extramammary Paget disease: A previously unreported neoplasm in the vulva and review of the literature [PDF]
Gynecologic Oncology ReportsThis report describes the first documented invasive acantholytic anaplastic extramammary Paget disease (AAEMPD) of the vulva. An 87-year-old female presented with a recurrent vulvar lesion refractory to topical imiquimod and treated with multiple wide ...
Flora Mae G. Sta. Ines +4 more
doaj +2 more sources
Insights Into Mammary and Extramammary Paget's Disease: Diagnosis, Management, and Recent Advances. [PDF]
CureusMammary Paget’s disease (MPD) and extramammary Paget’s disease (EMPD) are rare cutaneous disorders associated with adenocarcinoma, each presenting unique clinical challenges.
Ortuz Lessa C +5 more
europepmc +2 more sources
Extramammary Paget Disease: a Therapeutic Challenge, for a Rare Entity
Current Oncology Reports, 2023 Extramammary Paget disease (EMPD) is a rare entity which is more frequently localized at the vulva, though it only accounts for 1–2% of vulvar neoplasms.
Jesús Chamorro Pérez +6 more
semanticscholar +1 more source
Curative Effect of Cutaneous Ulcer Wound Repair Through a Novel Liquid Dressing After HpD-PDT Treatment of Extramammary Paget's Disease-A Prospective, Semi-Lesion Controlled, Pilot Study. [PDF]
J Cosmet DermatolABSTRACT Objective To evaluate the clinical efficacy and safety of a novel skin wound dressing in promoting the repair of the ulcer wound after the treatment of Extramammary Paget's Disease (EMPD) with Hematoporphyrin Derivative Photodynamic Therapy (HpD‐PDT).
Wang D +5 more
europepmc +2 more sources
TRPS1 expression is sensitive and specific for primary extramammary Paget disease
Histopathology, 2023 Extramammary Paget disease (EMPD) is an epithelial neoplasm that can occur at many sites, including the vulva and scrotum. EMPD is characterised by the presence of neoplastic cells, in single cells and clusters, that infiltrate all layers of non ...
Eleanor E Cook, B. Harrison, M. Hirsch
semanticscholar +1 more source
An Evaluation of HER2 Expression Heterogeneity in Primary Tumors and Metastatic Lymph Nodes of Patients With Advanced Extramammary Paget's Disease: Prognostic and Therapeutic Implications. [PDF]
Cancer MedABSTRACT Background HER2 expression in primary versus metastatic tumors in advanced Extramammary Paget's Disease (EMPD) remains inadequately characterized. This investigation aimed to assess HER2 expression heterogeneity between primary tumors and metastatic lymph nodes (LNs) in patients with advanced EMPD and to assess the prognostic value of HER2 ...
Liu Z +9 more
europepmc +2 more sources
Frontiers in Oncology, 2022 Extramammary Paget disease (EMPD) is a rare form of cutaneous, intraepithelial adenocarcinoma, which typically presents itself as an erythematous plaque originating from apocrine-gland rich regions, such as the vulva, the perianal region, the scrotum ...
E. Zattarin +11 more
semanticscholar +1 more source
Topical Imiquimod in Primary Cutaneous Extramammary Paget’s Disease: A Systematic Review
Cancers, 2023 Simple Summary The main treatment for extramammary Paget’s disease (EMPD) is still surgery, but this neoplasm usually spreads beyond the clinical surroundings of the lesion, and achieving histopathologically free margins can be challenging and requires ...
F. Mayo-Martínez +7 more
semanticscholar +1 more source
Cancer Medicine, 2023 Extramammary Paget's disease (EMPD) is rare. There are no standard treatments due to its rarity and few clinical trials.
B. Sohn +13 more
semanticscholar +1 more source
BJR|case reports, 2016 The purpose of this report is to describe an unusual case of extramammary Paget's disease with urethral and lymph node infiltration and demonstrate the role of MRI in the pre-operative period for the assessment, management and prognosis of the disease.
Vasquez, Andres +2 more
openaire +3 more sources