Results 21 to 30 of about 15,845 (183)

Clinicopathological characteristics and survival outcomes in Paget disease: a SEER population‐based study

open access: yesCancer Medicine, 2018
The objective of this study was to investigate the clinicopathological characteristics and survival outcomes of Paget disease (PD), Paget disease concomitant infiltrating duct carcinoma (PD‐IDC), and Paget disease concomitant intraductal carcinoma (PD ...
Yang Zhao   +6 more
doaj   +1 more source

Paget's disease of bone [PDF]

open access: yesThe Journal of Bone and Joint Surgery. British volume, 1979
This chapter focuses on Paget's disease of bone. The pathological hallmark of the Paget's bone disease is excessive and disorganized activity of bone that involves both matrix and mineral. There is no idea of its cause and little knowledge of its natural history; however, the biochemical changes produced by the overactive bone justify its inclusion as ...
openaire   +3 more sources

Establishment of a TNFRSF11B knock-out human induced pluripotent stem cell line (KSCBi002-B-2) via CRISPR/Cas9 system

open access: yesStem Cell Research, 2023
A TNFRSF11B (TNF Receptor Superfamily Member 11b) gene encodes a soluble decoy receptor, osteoprotegerin (OPG), which has a key role in repressing osteoclast differentiation. In this report, we generated a biallelic knock-out hiPSC line for the TNFRSF11B
Jujin Jeong   +4 more
doaj   +1 more source

Paget's Disease of the Bone [PDF]

open access: yesMedical Journal Armed Forces India, 2003
Paget's disease of bone (PDB) is a localised disorder of bone remodelling, characterised by enhanced resorption of bone by giant multinucleated osteoclasis followed by formation of disorganised woven bone by osteoblasts. The resultant bone is expanded, weak and vascular, causing bone pain brittleness and deformity.
K, Narayanan   +2 more
openaire   +2 more sources

Pigmented Paget′s disease of nipple: A diagnostic challenge on cytology

open access: yesJournal of Cytology, 2013
Paget′s disease is a rare form of breast cancer often associated with an underlying ductal carcinoma in situ or invasive cancer. A 47-year-old female patient presented with bleeding from the left nipple since 4 months.
B R Vani   +3 more
doaj   +1 more source

Pigmentary Mammary Paget Disease: clinical, dermoscopical and histological challenge

open access: yesDermatology Reports, 2021
A very rare variant of MPD is the Pigmented Mammary Paget Disease (PMPD), first described by Culberson et al. in 1956. It is very difficult to distinguish this variant from melanoma both clinically and dermoscopically.
Angelo Massimiliano D'Erme   +7 more
doaj   +1 more source

Paget bone disease demonstrated on 18F-fluorocholine PET/CT: a case report [PDF]

open access: yesBeyond Rheumatology, 2020
Paget disease (PD) is a chronic disorder resulting in enlarged and misshapen bones, caused by disorganized bone remodeling. This case involves a 64-year-old man with prostatic adenocarcinoma and PD of some skeletal areas with increased uptake shown on 18
Antonella Laria   +6 more
doaj   +1 more source

Paget's Disease of Bone [PDF]

open access: yesNew England Journal of Medicine, 1993
Paget's disease of bone may present with bone pain but is often asymptomatic. Treatment (typically with bisphosphonates) is indicated in patients with pain that is localized to an affected site but not in asymptomatic patients.
openaire   +3 more sources

Vulvar Paget disease secondary to high-grade urothelial carcinoma with underlying massive vascular embolization and cervical involvement: case report of unusual presentation

open access: yesDiagnostic Pathology, 2019
Background Vulvar extramammary Paget disease is a rare chronic condition, that presents with non-specific symptoms such as pruritus and eczematous lesions. Because most of these lesions are noninvasive, the distinction between primary and secondary Paget
Walquiria Quida Salles Pereira Primo   +5 more
doaj   +1 more source

Beyond the Ordinary: A Surgical Approach to Perianal Paget Disease

open access: yesJournal of Coloproctology
Perianal Paget Disease (PPD) is a rare form of extramammary Paget disease characterized by erythematous or eczematous plaques in the perianal region. Its rarity and resemblance to benign skin conditions often result in delayed diagnosis.
Rita Ribeiro Dias   +8 more
doaj   +1 more source

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