Results 121 to 130 of about 213,033 (304)

Circadian clock genes cause activation of the human PAI-1 gene promoter with 4G/5G allelic preference

, 2006
Increased plasminogen activator inhibitor-1 (PAI-1) activity is associated with greater risk of myocardial infarction. PAI-1 expression is regulated by a 4G/5G promoter polymorphism.
Veryan Codd, Codd, V., Chong, Nelson W., Samani, N.J., Danny Chan, Nilesh J. Samani, Nelson W. Chong, Chan, D.   +7 more
core   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Flexible wearable electronics for cardiovascular monitoring from surface signals to deep physiological insights

FlexMat, EarlyView.
This review organizes flexible wearable electronics for cardiovascular monitoring into four interconnected information layers: surface electrophysiology, hemodynamic sensing, vascular imaging, and biofluid biomarker analysis. This framework clarifies how electrical rhythm, vascular loading, structural and flow‐related features, and biochemical states ...
Qiao Chen, Hongwen Chen, Yuanyuan Li, Pingan Yang, Rui Li, Zhihao Zhou   +5 more
wiley   +1 more source

Craniofacial Resection for Advanced Cutaneous Squamous Cell Carcinoma: Results From the 2nd International Collaborative Case‐Series

Head &Neck, EarlyView.
ABSTRACT Background Robust outcome data for anterior skull base cutaneous squamous cell carcinoma (cSCC) are limited, particularly as emerging therapies reshape management. We evaluated survival and prognostic factors following craniofacial resection. Methods Retrospective multi‐institutional case‐series (1995–2015) of patients who underwent skull base
Michael J. C. Schachtel, Benedict J. Panizza, James J. Bowman, Catherine Barnett, Cristina Valero, Ian Ganly, Snehal G. Patel, Helena Levyn, Dauren Adilbay, Alana Eagan, Marc A. Cohen, Lillian A. Boe, Junting Zheng, Mithat Gonen, Prathamesh Pai, Paolo Castelnuovo, Fang Ju Gao, Cesare Piazza, Piero Nicolai, Luiz P. Kowalski, Ronaldo N. Toledo, Claudio Cernea, Sergio Goncalves, Dan M. Fliss, John R. de Almeida, Ian Witterick, Philippe Herman, Walter Fontanella, Gregorio Sanchez Aniceto, Alvaro Rivero Calle, Sefik Hosal, Serdar Ozer, Subramania Iyer, Richard J. Harvey, C. Rene Leemans, Jan‐Jaap Hendrickx, Marcelo Figari, Luis Boccalatte, Ken Ichi Nibu, Peter Clarke, Catherine Rennie, Yiming Zhu, Rodney J. Schlosser, Fernando L. Dias, Zoukaa Sargi, Shahzada Ahmed, Wojciech Golusinski, Se Heon Kim, Shirley Y. Su, Shaan M. Raza, Franco DeMonte, Ehab Hanna, Jatin P. Shah   +52 more
wiley   +1 more source

PAI-1 deficiency drives pulmonary vascular smooth muscle remodeling and pulmonary hypertension

Pulmonary arterial hypertension (PAH) is a progressive disease characterized by vasoconstriction and remodeling of small pulmonary arteries (PAs). Central to the remodeling process is a switch of pulmonary vascular cells to a proliferative, apoptosis ...
Douglas B Cines (20265111), Geoffrey Newcomb (20265093), Srimathi Bogamuwa (3179145), Mortimer Poncz (1560787), Sergei V Zaitsev (20265081), Joshua P McGuckin (20265084), Dmitry Goncharov (20265087), Iryna Zhyvylo (20265090), Victoria Stepanova (368577), Derek Lin (12966308), Elena A Goncharova (20265114), Bryce Piper (20265096), Benjamin J Buckley (20254644), Tatiana V Kudryashova (20265078), Michael J Kelso (20254647), Horace M DeLisser (20265108), Leyla Teos (20265102), Andressa Pena (12966314), Marie Ranson (25441), Lifeng Jiang (3283797), Aisha Saiyed (20265099), John R Greenland (20265105), Paul J Wolters (16372914), Laszlo Farkas (91352)   +23 more
core  

PERAN GURU PAI DALAM PEMBENTUKANAKHLAKUL KARIMAH DIMASA PANDEMI COVID-19DI SMP.IT AL-ASROR DESA SUMBERSARI KEC.SEKAMPUNG KAB. LAMPUNG TIMUR

, 2022
Peran Guru PAI Dalam Pembentukan Akhlakul Karimah Dimasa PandemiCovid-19 di SMP.IT Al-Asror Desa Sumbersari Kecamatan SekampungKabupaten Lampung TimurABSTRAKPada dasarnya tugas seorang guru adalah mengarahkan danmembentuk akhlak siswa bukan hanya sekedar
YUNIA EKA PUTRI NPM:193210253 Prodi: Pendidikan Agama Islam (PAI) Fakultas Tarbiyah
core  

A CONCEPÇÃO DO HOMEM NO EXERCÍCIO DA PATERNIDADE JUNTO AO TRANSTORNO DO ESPECTRO AUTISTA (TEA)

Revista Diálogos e Perspectivas em Educação Especial
O presente estudo teve por objetivo compreender a perspectiva paterna acerca do exercício da paternidade junto ao filho com diagnóstico de Transtorno do Espectro Autista (TEA). Para tanto, foi proposto um estudo qualitativo, exploratório e descritivo.
Aline Cristina de SOUZA
doaj   +1 more source

Mental health and healthcare use during COVID‐19 among neurodivergent youth and youth with pre‐existing psychiatric disorders: A systematic review

JCPP Advances, EarlyView.
Abstract Background Neurodivergent youth and youth with pre‐existing psychiatric disorders may have faced additional challenges in navigating the demands and restrictions of the COVID‐19 pandemic. However, less is known about how mental health outcomes and psychiatric healthcare utilization differed across diagnostic groups and other youth‐related ...
Ulyana Sirotina, Bryndis Lara Bjarnadottir, Agnieszka Butwicka, Eivind Ystrom, Jaana Suvisaari, Olli Kiviruusu, Audun Valborgarson, Heiddis Bjork Valdimarsdottir, Helga Ask, Unnur Valdimarsdottir, Thorhildur Halldorsdottir   +10 more
wiley   +1 more source

Nutritional and environmental determinants of maturation and disruption of the early life gut microbiome: A narrative review

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract The first 1000 days of life represent a critical window for gut microbiome assembly, with lifelong implications for child growth, immune development, and disease risk. This review synthesizes evidence on maternal, perinatal, and especially nutritional factors that influence early‐life intestinal colonization and highlights the consequences of ...
Carly Burow, Romy Shenderey, Fariha Chowdhury, Nyah Shah, Nikhil Pai   +4 more
wiley   +1 more source

URGENSI BAHAN AJAR PAIBAGI PESERTA DIDIK

, 2021
ABSTRAKURGENSI BAHAN AJAR PAIBAGI PESERTA DIDIKOleh:RIDA ANISTIYANPM. 15210137Pembelajaran merupakan suatu proses yang kompleks dan melibatkanberbagai aspek yang saling berkaitan.
RIDA ANISTIYA NPM: 15210137 Prodi: Pendidikan Agama Islam (PAI)
core