Results 141 to 150 of about 35,661 (228)

NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang   +8 more
wiley   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan   +9 more
wiley   +1 more source

Longitudinal Pancreaticojejunostomy Reconstruction Following Pancreaticoduodenectomy for Patients With Concomitant Chronic Pancreatitis: How I Do It

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 281-286, January 2026.
This report details a modified reconstructive technique, longitudinal pancreaticojejunostomy (LPJ), following pancreaticoduodenectomy (PD) for patients with both pancreatic head pathology and extensive chronic pancreatitis. This approach ensures wide‐area drainage of the remnant pancreatic duct, providing effective symptom relief and preserving long ...
Hideaki Sato   +4 more
wiley   +1 more source

Phytobezoar—An Unusual Cause of Small Bowel Obstruction in Pediatric Age Group: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Phytobezoars are the most common and well known type of bezoars yet one of the uncommon causes of mechanical obstruction of the small intestine. The reported prevalence rate of phytobezoars is estimated to be 0.4% despite being the 5th most common cause of acute small bowel obstruction.
Aakash Pandit   +3 more
wiley   +1 more source

Delayed Diagnosis of Tuberous Sclerosis Complex: A Case Report of Abdominal Distension, Pain, and Severe Anemia

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT We present a case of a 31‐year‐old woman with progressive abdominal distension, bilateral loin pain, and severe anemia requiring multiple blood transfusions. She was referred for a computed tomography (CT) scan of bilateral renal masses before potential surgery.
Hamim Rusheke   +3 more
wiley   +1 more source

A forgotten frontier: spinal cord stimulation for iatrogenic and traumatic peripheral neuropathic pain. [PDF]

open access: yesFront Pain Res (Lausanne)
Kollenburg L   +9 more
europepmc   +1 more source

Pregnancy complicated by a large prolapsing cervical fibroid requiring antepartum vaginal myomectomy—A case report

open access: yes
International Journal of Gynecology &Obstetrics, Volume 172, Issue 2, Page 1268-1270, February 2026.
Samantha Taylor   +2 more
wiley   +1 more source

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