Results 161 to 170 of about 89,513 (282)

Intractable Pain.

Annals of Internal Medicine, 1974
  +5 more sources

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, Volume 13, Issue 26, 8 May 2026.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Pediatric Area Postrema Cavernoma: Clinical Presentation With Hiccups and Vomiting. [PDF]

Cureus
Kaake A.
europepmc   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Advanced Science, Volume 13, Issue 27, 13 May 2026.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang, Rong Ren, Zhan Su, Jiahao Zhou, Pinyin Cao, Sicheng Zhang, Zhen Li, Chao Li, Songsong Zhu   +8 more
wiley   +1 more source

Ketamine as a Novel Solution for Opioid-Refractory Pain in Radiation Necrosis. [PDF]

Cureus
Campbell C, Ellis-Wittenhagen J, Murphy T.   +2 more
europepmc   +1 more source

Inhibiting cGAS‐STING to Preserve Mitochondrial–Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age‐Related Tendinopathy

Advanced Science, Volume 13, Issue 26, 8 May 2026.
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang, Weiyong Song, Heng Yin, Yi Wang, Yi Zou, Yuling Li, Yue Luo, Chao Xiang, Xiaoqin Liu, Yan Xiong, Yong Wang, Ke Jiang   +11 more
wiley   +1 more source

Practice advisory for intravenous management of headache disorders in hospitalized patients: a review of the evidence and consensus recommendations. [PDF]

Reg Anesth Pain Med
Hoydonckx Y, Feoktistov A, Amoozegar F, Anderson CC, Barad M, Burke E, Chitsantikul P, Doshi TL, Englesakis M, Goel A, Gupta H, Kissoon N, Kirschner A, Kohan L, Lauritsen CG, Miller F, Monsour D, Nader A, Ogunlaja O, Schuster N, Schwenk ES, Silberstein SD, Souza D, Yuan H, Narouze S.   +24 more
europepmc   +1 more source

Patient satisfaction and scope size of flexible ureteroscopy for upper urinary stones: A comparative study, multivariate analysis and subjective and objective evaluations

BJUI Compass, Volume 7, Issue 5, May 2026.
Abstract Objective This study aimed to evaluate subjectively and objectively the use of the slimmest scope, 7.5 Fr, on patient quality of life and outcome for upper urinary stones (UUS) treated by flexible ureteroscopy and to study the impact of ureteric stent insertion and operative techniques on patient satisfaction.
Ihab A. Hekal, Yousef I. Hekal, Jana I. Hekal, Abdulla Al Memari   +3 more
wiley   +1 more source

Clinical effectiveness of spinal cord stimulation in managing refractory upper-extremity pain. [PDF]

Neurosurg Rev
Ingkapassakorn Y, Vuttipongkul S, Sitthinamsuwan B, Jirachaipitak S, Euasobhon P, Zinboonyahgoon N, Nunta-Aree S.   +6 more
europepmc   +1 more source

Euthanasia: A Soft Paradigm for Medical Ethics [PDF]

, 1978
McIntyre, Russell L.
core   +1 more source