Results 61 to 70 of about 1,773,214 (340)

Neuromodulation in intractable pain management: outcomes and predictors of revisions of spinal cord stimulators.

open access: yesNeurosurgical Focus, 2016
OBJECTIVE Spinal cord stimulators (SCSs) appear to be safe and efficacious for chronic intractable back pain. Although there are many reports on percutaneous SCSs, there are very few studies on outcomes of paddle lead SCSs. In addition, the predictors of
S. Bir   +4 more
semanticscholar   +1 more source

3‐Year Outcomes of Temperature‐Controlled Radiofrequency Ablation of the Posterior Nasal Nerve in Patients With Chronic Rhinitis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Temperature‐controlled radiofrequency (TCRF) ablation of the posterior nasal nerve has been shown to improve chronic rhinitis (CR) symptoms and quality of life (QoL). This study assesses the durability of TCRF's effectiveness and safety 3 years post‐procedure in patients with perennial allergic CR and nonallergic CR.
J. Pablo Stolovitzky   +8 more
wiley   +1 more source

Perception threshold and electrode position for spinal cord stimulation [PDF]

open access: yes, 1994
The perception threshold for epidural spinal cord stimulation in chronic pain management was analyzed on 3923 testing data obtained from 136 implanted patients.
Barolat, Giancarlo   +3 more
core   +3 more sources

Euthanasia and physician-assisted suicide for patients with depression. Thought-provoking remarks [PDF]

open access: yes, 2020
Euthanasia and medical assistance in dying entail daunting ethical and moral challenges, in addition to a host of medical and clinical issues, which are further complicated in cases of patients whose decision-making skills have been negatively affected ...
Bersani, G   +3 more
core   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

open access: yesChemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui   +2 more
wiley   +1 more source

A-Type KV Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction [PDF]

open access: yes, 2018
A-type voltage-gated potassium (Kv) channels are major regulators of neuronal excitability that have been mainly characterized in the central nervous system. By contrast, there is a paucity of knowledge about the molecular physiology of these Kv channels
Covarrubias, Manuel   +3 more
core   +1 more source

Predictive Factors for Successful Outcome of Pulsed Radiofrequency Treatment in Patients with Intractable Lumbosacral Radicular Pain.

open access: yesPain medicine (Malden, Mass.), 2016
BACKGROUND In a previous prospective study on pulsed radiofrequency (PRF) treatment adjacent to the lumbar dorsal root ganglion (DRG) for patients with chronic lumbosacral radicular pain, we reported success in 55.4% of the patients at 6 months ...
K. Van Boxem   +6 more
semanticscholar   +1 more source

Efficacy and tolerability of perampanel as add‐on therapy in Dravet syndrome: A prospective real‐world study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To investigate the efficacy and tolerability of perampanel (PER) on Dravet syndrome in China by a prospective real‐world study. Methods We prospectively enrolled children with Dravet syndrome from the neurology clinic of Shenzhen Children's Hospital from September 2020 to October 2021.
Han Wang   +9 more
wiley   +1 more source

Eosinophilic Jejunitis Presenting as Intractable Abdominal Pain

open access: yesCase Reports in Gastroenterology, 2014
Eosinophilic gastroenteritis is an uncommon disease characterized by eosinophilic infiltration of the gastrointestinal tract. The clinical manifestations are related to the layer(s) and extent of the bowel involved.
Zeynel Mungan   +4 more
doaj   +1 more source

How Much Does It Hurt: A Deep Learning Framework for Chronic Pain Score Assessment [PDF]

open access: yesarXiv, 2020
Chronic pain is defined as pain that lasts or recurs for more than 3 to 6 months, often long after the injury or illness that initially caused the pain has healed. The "gold standard" for chronic pain assessment remains self report and clinical assessment via a biopsychosocial interview, since there has been no device that can measure it.
arxiv  

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