Results 61 to 70 of about 38,371 (241)

The Intraoperative Microlesion Effect Positively Correlates With the Short‐Term Clinical Effect of Deep Brain Stimulation in Parkinson's Disease

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange, Naomi I. Kremer, Teus van Laar, Fiete Lange, T. Elien Steendam‐Oldekamp, D. L. Marinus Oterdoom, Anthony R. Absalom, J. Marc C. van Dijk, Gea Drost   +8 more
wiley   +1 more source

Predictive Factors of Successful Spinal Cord Stimulation in Patients with Chronic Pain: A Retrospective Cohort Study

Brain Sciences
Background: Spinal cord stimulation (SCS) is applied for managing chronic intractable pain, but the factors predicting its effectiveness have not been extensively researched.
Yongjae Yoo, Hyungsang Roh, Jee Youn Moon, Eun Joo Choi, Francis Sahngun Nahm, Pyung Bok Lee   +5 more
doaj   +1 more source

Management of ketogenic diet therapy in patients with ileostomy: A report of 2 cases

Nutrition in Clinical Practice, EarlyView.
Abstract This case series explores the feasibility and clinical considerations of implementing the ketogenic diet therapy (KDT) for epilepsy management in patients with ileostomies. Two pediatric patients with medication‐resistant epilepsy and ileostomies continued KDT under clinical supervision.
Braden J. Baker, Abigail E. Olbina, Marissa A. Godfrey, Annie E. Graber, Taylor N. Parrish, Sarah Isis R. Delima   +5 more
wiley   +1 more source

Cognitive Outcome After Deep Brain Stimulation for Refractory Obsessive–Compulsive Disorder: A Systematic Review

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Introduction Deep brain stimulation (DBS) is an effective treatment for refractory obsessive–compulsive disorder (OCD). Neuropsychological assessment contributes to DBS treatment in several ways: it monitors the cognitive safety of the treatment, identifies beneficial or detrimental cognitive side effects and it could aid to explain ...
Tim A. M. Bouwens van der Vlis, Annelien Duits, Mégan M. G. H. van de Veerdonk, Anne E. P. Mulders, Koen R. J. Schruers, Yasin Temel, Linda Ackermans, Albert F. G. Leentjens   +7 more
wiley   +1 more source

Erector spinae plane block for intractable, nonsurgical abdominal pain: a scoping review [PDF]

Clinical and Experimental Emergency Medicine
Abdominal pain is one of the most common presenting chief complaints in the emergency department. Erector spinae plane block (ESPB) is an ultrasound-guided nerve block with proven effectiveness in treating visceral and somatic abdominal pain. Despite the
Ashley Meyer, Campbell Belisle Haley, Eisa Razzak, Amanda Dos Santos, Kyle Dornhofer, Edmund Hsu, Soheil Saadat, John Christian Fox, Megan Guy   +8 more
doaj   +1 more source

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

The Tragedy of Painless Needs

Pain Research and Management, 2000
Intractable pain demands the attention of both the patient and the physician. However, modern science and medicine cannot and should not promise the abolition of pain and suffering.
John D Loeser
doaj   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

VIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang, Junlei Chai, Quanwei Ding, Luping Liu, Kejie Zhang, Jie Lin, Jianhua Zhang, Youju Huang   +7 more
wiley   +1 more source

Longitudinal pancreatico-gastrostomy: An effective means of pain control in chronic pancreatitis

The Saudi Journal of Gastroenterology, 2007
Aim: To assess the effectiveness of longitudinal pancreatico-gastrostomy (LPG) in relieving intractable abdominal pain in patients of chronic pancreatitis (CP) with dilated main pancreatic duct (MPD).
Bhattacharjee Prosanta
doaj  

Views from the Inside: Reflections on the Modern Hospital

The Political Quarterly, EarlyView.
Abstract There's a constant refrain in the press, on social media and from populist politicians that the NHS is dying on its feet. How accurate is this picture? This article takes a behind‐the‐scenes look at daily life in a modern, big city hospital. The Queen Elizabeth is now the biggest workplace in Birmingham.
Jon Bloomfield
wiley   +1 more source