Results 121 to 130 of about 550,018 (287)

Electrosensitive Heterogeneous Short Fibers via Acousto‐Electric Coupling for Sequential Bone Regeneration in Infectious Defects

Advanced Science, EarlyView.
Electrosensitive heterogeneous short fibers can accurately respond to ultrasonic field regulation through the synergistic interaction of piezoelectric and conductive dual elements. At an ultrasound intensity of 1.5 W cm−2, it can effectively activate bacterial peroxisome and necrotic apoptotic pathway and promote bacterial apoptosis.
Xiaoyu Han, Fan Wang, Pengcheng Xiao, Zheng Yang, Mingyue Liu, Zeyu Han, Zijie Wang, Anan Jiang, Jindong Tan, Juan Wang, Wenguo Cui, Dingqun Bai   +11 more
wiley   +1 more source

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

Advanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl, Finn Jaekel, Julia Henne, Richard Kantelberg, Daniel C. Freund, Eberhard Grambow, Brigitte Vollmar, Amelie R. Zitzmann, Hans Kleemann, Jochen Hampe, Sebastian Hinz, Clemens Schafmayer, Karl Leo   +12 more
wiley   +1 more source

The Efficacy of Peripheral Opioid Antagonists in Opioid-Induced Constipation and Postoperative Ileus: A Systematic Review of the Literature. [PDF]

, 2017
Opioid-induced constipation has a negative impact on quality of life for patients with chronic pain and can affect more than a third of patients. A related but separate entity is postoperative ileus, which is an abnormal pattern of gastrointestinal ...
Baratta, Jaime L., Grant, Alexander E., McNulty, Stephen E., Schwenk, Eric S., Torjman, Marc C., Viscusi, Eugene R.   +5 more
core   +1 more source

Under‐Urine‐Adhered Supramolecular Hydrogel with Linearly Sustained Quercetin Release Facilitates Hemorrhagic Cystitis Healing via Inflammation Regulation

Advanced Science, EarlyView.
A supramolecular gelatin‐based hydrogel adhesive was engineered for hemorrhagic cystitis management. It provides robust wet‐tissue adhesion, rapid hemostasis, sustained quercetin release, effectively restoring the bladder barrier via anti‐inflammatory and antioxidant actions.
Xu Cao, Hua Zhang, Yang Luo, Yaoqi Chen, Jie Yao, Renhao Ni, Tong Zhu, Yudong Yao, Jun Chen, Baolin Guo, Kerong Wu   +10 more
wiley   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Analgesia pós-operatória

Revista do Colégio Brasileiro de Cirurgiões
JUSTIFICATIVAS E OBJETIVOS: A dor sempre foi uma das maiores preocupações do homem, entretanto, apesar dos progressos da ciência, ainda existem várias barreiras ao seu adequado tratamento, incluindo a falta de conhecimento por parte da equipe médica ...
Betina Sílvia Beozzo Bassanezi, Antonio Gonçalves de Oliveira Filho   +1 more
doaj   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

Advanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr., Georgii B. Telegin, Aleksandr S. Chernov, Anna A. Kudriaeva, Alexey N. Minakov, Maksim V. Rodionov, Vitaly A. Kazakov, Viktor A. Palikov, Yuri M. Poluektov, Rustam H. Ziganshin, Daria A. Orlova, Alena S. Evpak, Daniil A. Barsuk, Fedor A. Mesheryakov, Aldo Spallone, Dmitry S. Asyutin, Igor N. Pronin, Nikolay A. Konovalov, Dmitri Yu Usachev, Alexander G. Gabibov, Alexander N. Konovalov   +20 more
wiley   +1 more source

Abdominal-pelvic pain in female patients with endometriosis - a review of the literature [PDF]

, 2018
Abdominal-pelvic pain is the dominant symptom in endometriosis, one of the most common pathologies that affect women, being also a multifactorial disorder.
Andronache, Liliana Florina, Badiu, Cristinel Dumitru, Grigorean, Valentin Titus, Mandu, Mihaela, Mastalier, Bogdan, Mehedintu, Claudia, Paduraru, Dan Nicolae, Pantea Stoian, Anca Mihaela, Sima, Marina Romina   +8 more
core   +1 more source

Intelligent Sensing: The Emerging Integration of Machine Learning and Soft Sensors Based on Hydrogels and Ionogels

Advanced Science, EarlyView.
By integrating with machine learning (ML), hydrogel‐ and ionogel‐based soft sensors are gaining human brain‐like capabilities to perceive, learn, and predict. This review summarizes their advances, focusing on ML‐powered applications such as handwriting/gesture/object/motion/speech recognition, health monitoring, food detection, and beyond.
Wenqing He, Rumin Lin, Suixiu Kong, Mengyi Qiang, Lingqi Huang, Bing Dai, Xi Yao, Lei Su, Xueji Zhang   +8 more
wiley   +1 more source