Results 191 to 200 of about 203,517 (263)

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang   +6 more
wiley   +1 more source

The introduction of a value‐based reimbursement programme—Alignment and resistance among healthcare providers

open access: yesThe International Journal of Health Planning and Management, Volume 38, Issue 1, Page 129-148, January 2023., 2023
Abstract Reimbursement programmes are used to manage care through financial incentives. However, their effects are mixed and the programmes can motivate behaviour that goes against professional values. Value‐based reimbursement programmes may better align professional values with financial incentives.
Thérèse Eriksson   +2 more
wiley   +1 more source

Towards Polymer Composite‐Based Transient Electronic Systems

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biodegradable electronic systems are gaining attention for implantable biomedical applications, targeting disease treatment and lifespan extension. This review covers advances in biocompatible, biodegradable polymer composites using synthetic and natural polymers with conductive, semiconductive, and insulating fillers.
Gwan‐Jin Ko   +5 more
wiley   +1 more source

Selection of DNA Aptamers Against Parathyroid Hormone for Electrochemical Impedimetric Biosensor System Development

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT This work presents the pioneering development of an aptamer‐based electrochemical biosensor for real‐time monitoring of parathyroid hormone (PTH) levels, with a focus on intraoperative assessment during parathyroid surgery. It introduces, for the first time, the selection and characterization of aptamers targeting distinct segments of the PTH ...
Reza Didarian   +5 more
wiley   +1 more source

Safe recovery after cesarean in rural Africa: Technical consensus guidelines for post‐discharge care

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 160, Issue 1, Page 12-21, January 2023., 2023
Abstract Despite increasing cesarean rates in Africa, there remain extensive gaps in the standard provision of care after cesarean birth. We present recommendations for discharge instructions to be provided to women following cesarean delivery in Rwanda, particularly rural Rwanda, and with consideration of adaptable guidelines for sub‐Saharan Africa ...
Fredrick Kateera   +13 more
wiley   +1 more source

Paracetamol and its metabolites in children and adults with spinal muscular atrophy – a population pharmacokinetic model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao   +14 more
wiley   +1 more source

Translabial ultrasound evaluation after tension‐free transobturator tape technique: Outcomes based on the tape's position

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 160, Issue 1, Page 214-219, January 2023., 2023
Abstract Objective The purpose of this study was to evaluate the feasibility and accuracy of postoperative translabial ultrasound to assess the position of the tape implanted with the tension‐free transobturator tape technique. Methods We enrolled women with clinically and urodynamically proven type I or II stress urinary incontinence who were referred
Giorgio Gugliotta   +5 more
wiley   +1 more source

Trends in gabapentinoid prescribing: A nationwide Danish drug utilization study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Pregabalin and gabapentin are increasingly used for pain and other conditions. Concerns exist about overuse as well as potential misuse and abuse. To guide rational prescribing practices, we provide detailed nationwide data on the use of gabapentinoids in Denmark.
Anton Pottegård   +7 more
wiley   +1 more source

Postoperative morphologic changes of the isthmocele and clinical impact in patients treated by channel‐like (360°) hysteroscopic technique

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 160, Issue 1, Page 326-333, January 2023., 2023
Abstract Objective To evaluate the changes in (1) residual myometrial thickness (RMT), (2) cesarean scar defect (CSD) size, and (3) clinical symptoms, before and after channel‐like (360°) hysteroscopic resection for the treatment of CSD. Methods A single‐center, observational, prospective, cohort study was carried out enrolling all symptomatic patients
Paolo Casadio   +16 more
wiley   +1 more source

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