Results 41 to 50 of about 379,428 (261)

Use of gabapentin in management of postoperative pain after crosslinking

Revista Brasileira de Oftalmologia, 2021
Objective: The objective was to evaluate the efficacy of gabapentin in the management of neuropathic pain in patients with keratoconus, who were treated with fast (10 minutes) epi-off corneal crosslinking (CXL).
Ricardo Alexandre Stock, Jéssica Lays Gaio, Guilherme Moretto, Breno Grossi, Rafael André Mergener, Elcio Luiz Bonamigo   +5 more
doaj   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Does surgical procedure type impact postoperative pain and recovery in deep inferior epigastric artery perforator flap breast reconstruction?

Archives of Plastic Surgery, 2020
Background The deep inferior epigastric artery perforator (DIEP) flap is the commonest flap used for breast reconstruction after mastectomy. It is performed as a unilateral (based on one [unipedicled] or two [bipedicled] vascular pedicles) or bilateral ...
Alexander A. Azizi, Anita T. Mohan, Taj Tomouk, Elizabeth B. Brickley, Charles M. Malata   +4 more
doaj   +1 more source

N, S Co‐Doped Carbon Quantum Dots‐Riboflavin Composite Photosensitizers for Enhanced Iontophoresis‐Assisted Corneal Cross‐Linking

Advanced Science, EarlyView.
This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu, Yong Liu, Wenjing Zhang, Qiuruo Jiang, Yi Jin, Liangzheng Lin, Lumeng Wang, Zhanhao Gu, Mimi Lin, Shihao Chen   +9 more
wiley   +1 more source

Acute postoperative pain [PDF]

Romanian Journal of Medical Practice, 2016
Acute postoperative pain is a personal unpleasant sensory and emotional experience with negative physiological and psychological effects. Severe acute pain may increase postoperative morbidity and mortality and is a risk factor for chronic pain incidence.
Adriana Alexandra BRĂDIŞ, Adrian Daniel TULIN, Erick NESTIANU, Ioana Anca BĂDĂRĂU   +3 more
doaj   +1 more source

Selected Factors Influencing the Intensity of Postoperative Pain in Patients after Orthopedic and Gynecological Surgeries

Medicina, 2022
Currently, pain is considered the fifth vital sign, and its effective relief is a priority in many surgical departments. The aim of this study was to determine the influence of selected factors on the intensity of postoperative pain after orthopedic and ...
Klaudia Banaś, Paweł Więch, Patrycja Trojnar, Edyta Guty, Mateusz Skórka, Małgorzata Soroń, Anna Nowak, Dariusz Bazaliński   +7 more
doaj   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Interpleural analgesia with Morphine and Bupivacaine in pneumothorax

Universidad Médica Pinareña, 2019
Introduction:interpleural block offers postoperative analgesia with significant results in surgical interventions. Objective:to evaluate the benefits of interpleural block with 0.5 % Bupivacaine and Morphine by means of interpleural catheter in patients
Marcos Osuna Ramos, Alejandro Muñoz García, Adrián Alejandro Vitón-Castillo, Celia Fundora-González, Ana Lourdes Martínez Zamora   +4 more
doaj   +2 more sources

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

A smart device application for acute pain service in surgical patients at a tertiary hospital in South Korea: a prospective observational feasibility study [PDF]

Anesthesia and Pain Medicine
Background Pain assessment and patient education are essential for successful postoperative pain management. However, the provision of personnel for performing these tasks is often insufficient.
Soo-Hyuk Yoon, Susie Yoon, Da Som Jeong, Minah Lee, Eunju Lee, Young Jae Cho, Ho-Jin Lee   +6 more
doaj   +1 more source