Results 81 to 90 of about 6,329,531 (295)
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
, 2020 Chest Pain: Advanced Assessment and Management promotes a systematic approach to the assessment and management of patients presenting with chest pain and ..
Quinn, TJ
core +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
The Complexities of Nurses’ Pain Assessment in Hospitalized Preverbal Children
, 2019 Background: Preverbal children are at increased risk for underassessment of pain. Pain is a social transaction involving the child in pain and the nurse assessor. However, our understanding of the nurse's part in this transaction is limited.
Andersen, RD +13 more
core +1 more source
The effectiveness of an acceptance and commitment therapy self-help intervention for chronic pain [PDF]
, 2010 Objective: To evaluate the effectiveness of an Acceptance Commitment Therapy based self-help book for people with chronic pain. Method: This was a randomized 2 group study design.
Shennan, Jeannette +15 more
core +1 more source
Nursing Clinics of North AmericaPain is a universal human experience, yet is uniquely subjective, complex, and multifactorial. As the perception of pain is influenced by psychological, emotional, and cultural factors, it is imperative that health care providers utilize both subjective and objective assessment tools while also considering the psychological, cultural, and emotional ...
Stretanski MF, Stinocher S, Grandhe S.
europepmc +3 more sources
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Post-operative Pain: A Trial of a Pain Assessment Tool
, 1988 This study arose from a concern at the lack of knowledge of how nurses made pain assessments and at the lack of documentation of pain monitoring. We set out to trial a pain assessment tool to see if it was of benefit in assessment and management of the ...
Chris Tuffnell
core
Aging and Cancer, EarlyView.In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara +3 more
wiley +1 more source