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, 2015 Chronic pain is one of the most debilitating and expensive diseases, yet current therapies are often insufficient in bringing about long-term relief. Further, many treatments for chronic pain also carry significant side effects. The molecule adenosine has long been identified as a potent inhibitor of nociceptive circuits in the spinal cord; however ...
Sarah E. Street, Nathaniel A. Sowa
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Acta Anaesthesiologica Scandinavica, 1997
AbstractThe antinociceptive actions of adenosine and adenosine analogs in animal models has been known for more than 10 years. The recent development with regard to the pain modulatory effects of adenosine, primarily in clinical studies, has generated a renewed interest in this principle for pain control. This review summarizes the current knowledge in
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AbstractThe antinociceptive actions of adenosine and adenosine analogs in animal models has been known for more than 10 years. The recent development with regard to the pain modulatory effects of adenosine, primarily in clinical studies, has generated a renewed interest in this principle for pain control. This review summarizes the current knowledge in
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Progress in Neurobiology, 2002
Upon receipt in the dorsal horn (DH) of the spinal cord, nociceptive (pain-signalling) information from the viscera, skin and other organs is subject to extensive processing by a diversity of mechanisms, certain of which enhance, and certain of which inhibit, its transfer to higher centres.
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Upon receipt in the dorsal horn (DH) of the spinal cord, nociceptive (pain-signalling) information from the viscera, skin and other organs is subject to extensive processing by a diversity of mechanisms, certain of which enhance, and certain of which inhibit, its transfer to higher centres.
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Serotonin in Pain and Pain Control
2010Abstract In pain processing and modulation, serotonin (5-hydroxtryptamine, 5-HT) has excitatory (hyperalgesic) and inhibitory (analgesic) actions, depending on the site of action, the cell type and the type of receptor. In the periphery, 5-HT sensitizes afferent nerve fibers, thus contributing to inflammatory and neuropathic hyperalgesia.
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The Control of Pain in the Hand
Archives of Surgery, 1962From the patient's point of view, pain is the most important symptom encountered in hand problems. Successful control of pain hinges upon an understanding of the available methods of treatment. Physicians who are actively interested in hand problems learn how to cope with pain through scattered reference material, experience, and word-of-mouth teaching.
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Journal of Palliative Medicine, 2003
A38-YEAR-OLD PHILIPPINA WOMAN was admitted to an inpatient hospice unit with severe pain. She was a poor historian. She described the pain as shooting from her left hip radiating down the lateral aspect of her left leg to her left great toe. The pain was episodic.
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A38-YEAR-OLD PHILIPPINA WOMAN was admitted to an inpatient hospice unit with severe pain. She was a poor historian. She described the pain as shooting from her left hip radiating down the lateral aspect of her left leg to her left great toe. The pain was episodic.
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Nursing Older People, 2013
Follow us at: Visit us at: www.twitter.com/NScomment Nursing Older People Editor Lisa Berry Tel: +44 (0)20 8872 3169 Email: lisa.berry@rcnpublishing.co.uk Managing director/publisher Rhonda Oliver Editor in chief Jean Gray Senior editor Gary Bell Assistant editor Sophie Blakemore Senior production editor Julie Hickey Production editor Karen Davies ...
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Follow us at: Visit us at: www.twitter.com/NScomment Nursing Older People Editor Lisa Berry Tel: +44 (0)20 8872 3169 Email: lisa.berry@rcnpublishing.co.uk Managing director/publisher Rhonda Oliver Editor in chief Jean Gray Senior editor Gary Bell Assistant editor Sophie Blakemore Senior production editor Julie Hickey Production editor Karen Davies ...
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Pain Control Interventions in Preterm Neonates: A Randomized Controlled Trial
Indian Pediatrics, 2018V. Shukla +6 more
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