Results 91 to 100 of about 8,115 (216)
United European Gastroenterology Journal, Volume 13, Issue 9, Page 1678-1689, November 2025.ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, mainly due to its aggressive nature, early metastasis, diagnosis at late stages, and limited response to systemic anticancer therapy. Perineural invasion (PNI), defined as the infiltration of neoplastic cells along nerve fibers and within nerve sheaths, is ...
Martin Lovecek +10 more
wiley +1 more source
Disability, Subject‐Dependence, and the Bad‐Difference View
Bioethics, Volume 39, Issue 9, Page 802-809, November 2025.ABSTRACT Philosophers have debated on the “mere‐difference” view of disability, according to which disability as such is neutral in terms of well‐being, just like race and gender. It is contrasted with the “bad‐difference” view, which holds that disability is bad for its possessor even in a non‐ableist situation.
Shu Ishida +2 more
wiley +1 more source
Congenital Insensitivity to Pain with Anhidrosis in an Iranian Patient
Basic and Clinical Neuroscience, 2013 Congenital insensitivity to pain with anhidrosis is a rare disease of the nervous system which causes one to lose their feeling of pain. The disease is subtype four of hereditary sensory and autonomic neuropathy (HSAN IV) that results from NTRK1 gene ...
Nasrollah Saleh-gohari +1 more
doaj +2 more sources
A Pain in the Brain: How PACAP CeA Infusion Alters Mechanical and Thermal Sensitivity [PDF]
, 2015 Pain is a universal experience, yet the treatment of pain continues to challenge the medical community. The first step toward treating pain is understanding the underlying neurological mechanisms that lead to the perception of pain.
Huessy, Julia Grace
core +1 more source
Case Reports in Anesthesiology, 2018 A patient with congenital insensitivity to pain with anhidrosis (CIPA) underwent revision of total hip arthroplasty under general anesthesia with only propofol.
Yuki Sugiyama +4 more
doaj +1 more source
Consciously feeling the pain of others reflects atypical functional connectivity between the pain matrix and frontal-parietal regions [PDF]
, 2017 Around a quarter of the population report ‘mirror pain’ experiences in which bodily sensations of pain are elicited in response to viewing another person in pain.
Banissy, Michael J +3 more
core +1 more source
Neglected painless wounds in a child with congenital insensitivity to pain
The Pan African Medical Journal, 2014 A 13-year-old boy was brought by his mother for neglected toes wounds. There was a history of self-mutilation from first years of life with absence of normal reaction to painful stimuli. He had scars from injuries and he had self-mutilation of the distal
Ali Akhaddar, Mohamed Malih
doaj +1 more source
Phenomenal knowledge why: the explanatory knowledge argument against physicalism [PDF]
, 2019 Phenomenal knowledge is knowledge of what it is like to be in conscious states, such as seeing red or being in pain. According to the knowledge argument (Jackson 1982, 1986), phenomenal knowledge is knowledge that, i.e., knowledge of phenomenal facts ...
Mørch, Hedda Hassel
core
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels [PDF]
, 2015 Voltage-gated ion channels (VGICs) are membrane proteins that switch from a closed to open state in response to changes in membrane potential, thus enabling ion fluxes across the cell membranes.
Alessandro eMedoro +7 more
core +2 more sources
SCN9A channelopathy associated autosomal recessive Congenital Indifference to Pain : a case report
, 2017 Background: Congenital Indifference to Pain (CIP) is a rare condition that inhibits the ability of patients to perceive physical pain but otherwise keeps normal sensory modalities.
Cauwels, Rita +3 more
core +1 more source