Results 71 to 80 of about 8,066 (214)

Congenital Insensitivity to Pain: A Fatal Entity

Indian Journal of Medical Specialities
Congenital insensitivity to pain (CIP), also known as congenital analgesia, is an autosomal recessive, extraordinarily rare condition, in which a patient cannot feel pain in any part of his or her body.
Debojit Biswas, Paramita Thander, Moumita Pati, Pankaj Halder   +3 more
doaj   +1 more source

Anesthetic management of a patient with congenital insensitivity to pain with anhidrosis by coadministration of remifentanil

JA Clinical Reports, 2018
Background Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disease characterized by unexplained fever, systemic insensitivity to pain, anhidrosis, and mental distress.
Yoko Takeuchi, Yoshihito Fujita, Takeshi Shimomura, Shuji Kurokawa, Hiroki Noguchi, Yoshihiro Fujiwara   +5 more
doaj   +1 more source

NGF – the TrkA to successful pain treatment [PDF]

, 2012
Chronic pain arising from various pathological conditions such as osteoarthritis, low back or spinal injuries, cancer, and urological chronic pelvic pain syndromes presents significant challenges in diagnosis and treatment.
Kumar, Vinayak, Mahal, Brandon
core   +1 more source

Hypnotic analgesia reduces brain responses to pain seen in others. [PDF]

, 2017
Brain responses to pain experienced by oneself or seen in other people show consistent overlap in the pain processing network, particularly anterior insula, supporting the view that pain empathy partly relies on neural processes engaged by self ...
A Krishnan, A Öhman, AR Aron, BC Bernhardt, BE Depue, C Corradi-Dell’Acqua, C Lamm, C Lamm, D Kleinböhl, F Vignemont De, GD Iannetti, J Decety, JT Buhle, JW Peirce, K Friston, LE Simons, M Faymonville, M Faymonville, MC Anderson, MV Saarela, N Danziger, OM Klimecki, P Rainville, RE Shor, RH Gracely, T Singer, T Singer, TD Wager, V Legrain, WK Simmons, Y Cojan, Y Cojan   +31 more
core   +4 more sources

Exploring Pain Researcher and Clinician Perceptions of Complementary, Alternative, and Integrative Medicine: A Large‐Scale, International Cross‐Sectional Survey

Pain Practice, Volume 26, Issue 4, April 2026.
ABSTRACT Introduction Complementary, alternative, and integrative medicine (CAIM) has gained popularity among patients experiencing pain, used alongside conventional medical treatments. This study aimed to explore the perceptions of pain clinicians and researchers on CAIM interventions.
Jeremy Y. Ng, Dennis Anheyer, Holger Cramer   +2 more
wiley   +1 more source

Therapeutic opportunities for targeting cold pain pathways [PDF]

, 2015
Cold pain is a frequent symptom in neuropathic pain. Compared to other pain modalities, such as heat pain, the mechanisms behind physiological and pathological cold pain remain elusive.
Lewis, Richard J., Vetter, Irina, Yin, Kathleen, Zimmermann, Katharina   +3 more
core   +1 more source

Beyond a Conduit: The Evolution of Functional Biliary Stents From Active Intervention to Enabling Platforms

iNew Medicine, Volume 2, Issue 1, March 2026.
This review traces the evolution of functional biliary stents, outlining the paradigm shift from “active intervention” strategies that target stent failure to next‐generation “enabling platforms.” These platforms leverage biodegradable materials, 3D/4D printing, and smart sensors to achieve personalized, regenerative, and theranostic solutions ...
Muhan Li, Xu Liu, Xin Ye, Zhixia Dong, Xinjian Wan   +4 more
wiley   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, Volume 16, Issue 2, Page 252-267, February 2026.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

A Systematic Review of Congenital Insensitivity to Pain, a Rare Disease [PDF]

Journal of Personalized Medicine
Raquel Rodríguez Blanque, Juan Carlos Sánchez-García, Andrés Reinoso Cobo   +2 more
exaly   +1 more source

The good of boredom [PDF]

, 2018
I argue that the state of boredom (i.e., the transitory and non-pathological experience of boredom) should be understood to be a regulatory psychological state that has the capacity to promote our well-being by contributing to personal growth and to the ...
Elpidorou, Andreas
core