Results 61 to 70 of about 8,066 (214)

[Congenital pain insensitivity].

Boletin medico del Hospital Infantil de Mexico, 1981
A case showing multiple lesions that make it very illustrative is reported. Differential diagnosis is made with some other diseases that are similar in some isolated facts. Mention is also made on the pathophysiology of the disease as well as on the necessity of the intercourse of several medicosurgical specialties in the management of these patients ...
A, Redón Tavera, E, Fernández Herrera, D, Félix Acevedo   +2 more
openaire   +1 more source

Blended Support of Attachment in Families: A Case Study of FamilieLink

Journal of Family Therapy, Volume 48, Issue 2, May 2026.
ABSTRACT Attachment ruptures, when children struggle to trust in parental availability and support, are linked to increased risk of psychopathology. Preventing or repairing these ruptures is important for fostering secure attachment and promoting family mental health.
Marlies Wintmolders, Tom Van Daele, Marian J. Bakermans‐Kranenburg, Guy Bosmans   +3 more
wiley   +1 more source

Pain: A Necessary Evil? (Anesthetic Management of Congenital Pain Insensitivity Syndrome)

Indian Journal of Pain
Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal disorder. It is characterized by systemic insensitivity to pain, unexplained fever, and psychiatric manifestations.
Swati Keshav Vijapurkar, Sandeep Gade, Khushbu Karoo, Amrita Rath   +3 more
doaj   +1 more source

A rare case of congenital insensitivity to pain with anhydrosiss

Indian Journal of Pain, 2015
Congenital insensitivity to pain syndrome with anhydrosis (CIPA) is a rare inherited disorder. It is characterized by loss of pain and temperature sensation, lack of sweating and mild mental retardation.
Govardhani Yanamadala, Varaprasad Ussa, Pavani Medisetty, Bhavya Gatte   +3 more
doaj   +1 more source

An Inversion Disrupting FAM134B Is Associated with Sensory Neuropathy in the Border Collie Dog Breed [PDF]

, 2016
Sensory neuropathy in the Border Collie is a severe neurological disorder caused by the degeneration of sensory and, to a lesser extent, motor nerve cells with clinical signs starting between 2 and 7 months of age.
Beltran, E, De Risio, L, Forman, O P, Gutierrez-Quintana, R, Hitti, R J, Jenkins, C A, Mellersh, C, O'Brien, D P, Pettitt, L, Shelton, G D   +9 more
core   +4 more sources

Identification and Functional Characterization of Novel and Recurrent NTRK1 Variants in Chinese Families With Congenital Insensitivity to Pain With Anhidrosis: A Combined Clinical, Genetic, and Functional Study

European Journal of Neurology, Volume 33, Issue 5, May 2026.
This study investigates four Chinese families with congenital insensitivity to pain with anhidrosis (CIPA). Through next‐generation sequencing, we identified seven NTRK1 variants, including two novel mutations. Functional characterization of five identified missense and indel variants revealed distinct disruptions in the NGF‐TrkA pathway, ranging from ...
Yaqiong Ren, Yue Cao, Fangfang Cheng, Jin Dai, Yuan Zhang, Xinxin Wang, Jiali Chen, Lijun Zhou, Xiaoxiang Song, Hongying Wang   +9 more
wiley   +1 more source

Agency, qualia and life: connecting mind and body biologically [PDF]

, 2017
Many believe that a suitably programmed computer could act for its own goals and experience feelings. I challenge this view and argue that agency, mental causation and qualia are all founded in the unique, homeostatic nature of living matter.
A Damasio, A Pross, AM Turing, B Russell, C Gallistel, CS Carver, CS Carver, DM MacKay, E Nagasako, ED Schneider, G Mather, H Jonas, H Oshima, I Prigogine, J Gribbin, J Kim, J Kim, J Sachs, J Winston, JM Simmons, K Richter, M Born, M Kinoshita, M Raichle, N Block, N Yanofsky, P Johnson-Laird, P Machamer, P Shizgal, R Marken, RG Heath, S Bensmaia, WT Powers, X Barandarian   +33 more
core   +1 more source

Precision Under Pressure: Scalp Block and Dexmedetomidine for Brain Abscess Drainage in a Patient With Complex Cyanotic Heart Disease

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Cyanotic heart disease is a known risk factor for brain abscess. Anesthesia for burr‐hole drainage in these patients can be challenging due to complications like an increase in right‐to‐left shunt, arrhythmias, heart failure, and paradoxical air embolism. The risk of these complications can be decreased by choosing a scalp block with conscious
Sandeep Khatri, Ashish Raj Tiwari, Barsha Karki, Manisha Poudel, Anish Sah   +4 more
wiley   +1 more source

Congenital insensitivity to pain: Case report of a rare entity

Indian Journal of Paediatric Dermatology, 2018
Hereditary sensory and autonomic neuropathies (HSANs) are a group of disorders characterized by insensitivity to noxious stimuli and autonomic dysfunction, associated with pathological abnormalities of the peripheral nerves.
Swati Dahiya, Kondajji Ramchandra Vijayalakshmi, Mubeen Khan   +2 more
doaj   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

MedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai, Chongxiang Wang, Ping Jiang, Xiaopeng Mei   +3 more
wiley   +1 more source