Results 31 to 40 of about 418,561 (266)

Moderating effects of humanistic care and socioeconomic status on the relationship among pain intensity, psychological factors, and psychological function in adults with cancer pain from a province of China: A cross-sectional study

Frontiers in Psychiatry, 2023
ObjectiveThe objective of this study is to explore whether humanistic care practiced by clinical pharmacists and socioeconomic status moderate the associations among pain intensity, psychological factors (catastrophizing and resilience), and ...
Shuyun Wang, Xuyan Wang, Xiaohong Liu, Chenxing Zhao, Jinju Duan   +4 more
doaj   +1 more source

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams

Journal of Visualized Experiments, 2023
To quantify an individual's subjective pain severity, standardized pain rating scales such as the numeric rating scale (NRS), visual analog scale (VAS), or McGill pain questionnaire (MPQ) are commonly used to assess pain on a numerical scale. However, these scales are often biased and fail to capture the complexity of pain experiences.
Kwong, Jereen, Lin, Joanna, Leriche, Ryan, Wozny, Thomas A., Shaughnessy, Ana, Schmitgen, Ashlyn, Shirvalkar, Prasad   +6 more
openaire   +3 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Pressure pain threshold and pain perception in temporomandibular disorder patients: is there any correlation?

Revista Dor
BACKGROUND AND OBJECTIVES: Physical evaluation of temporomandibular disorder patients commonly includes evaluation of pain response to muscular and articular palpation and there is a considerable uncertainty of how self-reported pain intensity relates to
Juliana Stuginski-Barbosa, Rafael Santos Silva, Carolina Ortigosa Cunha, Leonardo Rigoldi Bonjardim, Ana Cláudia de Castro Ferreira Conti, Paulo César Rodrigues Conti   +5 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Relationship of Child Perceptions of Maternal Pain to Children’s Laboratory and Nonlaboratory Pain

Pain Research and Management, 2008
Previous research has established links between parent and child pain. However, little is known about sex-specific parent-child pain relationships in a nonclinical population.
Subhadra Evans, Jennie CI Tsao, Lonnie K Zeltzer   +2 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Abdominal pressure pain thresholds correlate with postoperative pain intensity

Science Progress
Objective We aim to investigate the correlation between ongoing pain levels and pain threshold measured by algometry after bariatric surgery. Methods A retrospective analysis was conducted on data from 150 patients who underwent bariatric surgery ...
Erfan Ghanad, Christel Weiss, Niki Taebi, Jasmin Klick, Sophie Staff, Alida Finze, Martin Dusch, Christoph Reissfelder, Martin Schmelz, Cui Yang   +9 more
doaj   +1 more source

Predictors of Analgesic Consumption in Orthodontic Patients

Applied Sciences, 2022
During orthodontic treatment, pain is a subjective experience influenced by several factors. Orthodontic patients consume analgesics at different rates to alleviate this pain. Correlations between orthodontic pain and analgesic consumption were analyzed.
Jovana Juloski, Dina Vasovic, Ljiljana Vucic, Tina Pajevic, Nevena Gligoric, Mladen Mirkovic, Branislav Glisic   +6 more
doaj   +1 more source