Results 61 to 70 of about 10,325,823 (284)

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Dietary pattern index and sleep disturbances: findings from the 2011–2014 National Health and Nutrition Examination Survey (NHANES)

BMC Public Health
Background Sleep disturbances have become an increasingly prevalent public health concern, with higher incidence rates observed among individuals with chronic conditions such as obesity and diabetes.
Yao Xiao, Yuehong Wu, Can Wang, Jianmin Dong, Ximing Zhang, Zhiyou Peng, Yunfei Cao   +6 more
doaj   +1 more source

Twelve-month results from a randomized controlled trial comparing differential target multiplexed spinal cord stimulation and conventional spinal cord stimulation in subjects with chronic refractory axial low back pain not eligible for spine surgery

North American Spine Society Journal
: Background: Successful treatments for intractable chronic low back pain (CLBP) in patients who are not eligible for surgical interventions are scarce.
Thomas White, MD, Rafael Justiz, MD, Wilson Almonte, MD, Velimir Micovic, MD, Binit Shah, MD, Eric Anderson, MD, Leonardo Kapural, MD, PhD, Harold Cordner, MD, Amr El-Naggar, MD, Michael Fishman, MD, MBA, Yashar Eshraghi, MD, Philip Kim, MD, Alaa Abd-Elsayed, MD, Krishnan Chakravarthy, Yoann Millet, MD, Mahendra Sanapati, MD, Nathan Harrison, MD, Brandon Goff, DO, Mayank Gupta, MD, Prabhdeep Grewal, MD, Michael Wilkinson, MD, Richard Bundschu, MD, Andrew Will, MD, Pankaj Satija, MD, Sean Li, MD, Scott Dulebohn, MD, John Broadnax, MD, Gennady Gekht, MD, Ken Wu, MD, Steven Falowski, MD, Wesley Park, MPH, David L. Cedeno, PhD, Ricardo Vallejo, MD, PhD   +32 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Retracted: Effects of Scrambler Therapy in Patients with Failed Back Surgery Syndromes and Factors Associated with Depression Affecting Pain before and after the Therapy

Pain Research and Management, 2021
Pain Research and Management
doaj   +1 more source

Effects of Transcutaneous Electrical Acupoint Stimulation on the Incidence of Hypoxia in Elderly Patients Undergoing Painless Gastrointestinal Endoscopy: A Randomized Controlled Trial

Pain Research and Management
Conclusion: TEAS can reduce the incidence of hypoxia in elderly patients undergoing painless gastrointestinal endoscopy.
Wenyu Zhou, Yu Wang, Pengcheng Ye, Song Hu, Siyu Li, Mingxia Wang, Duanyang Sheng, Yuanli Chen, Wang Shen, Yi Zhang, Feng Liu, Wei Zhang, Xin Lv, Xiangrui Wang, Hao Yang   +14 more
doaj   +1 more source

UK back pain exercise and manipulation (UK BEAM) trial - national randomised trial of physical treatments for back pain in primary care: objectives, design and interventions [PDF]

, 2003
Low back pain has major health and social implications. Although there have been many randomised controlled trials of manipulation and exercise for the management of low back pain, the role of these two treatments in its routine management remains ...
null null, UK Beam (Back pain Exercise and Manipulation) Trial Team, Burton, A. Kim   +2 more
core   +2 more sources

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source