Results 81 to 90 of about 1,893,963 (378)
Mika M Rockholt,1 Gifty Addae,1 Alexander Chee,1 Wanda Chin,1 Germaine Cuff,1 Jing Wang,1,2 Uchenna O Umeh,1,3 Lisa V Doan1 1Department of Anesthesiology, Perioperative Care and Pain Management, New York University Grossman School of Medicine, New York ...
Rockholt MM+7 more
doaj
Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs [PDF]
We endeavored to identify objective blood biomarkers for pain, a subjective sensation with a biological basis, using a stepwise discovery, prioritization, validation, and testing in independent cohorts design. We studied psychiatric patients, a high risk
Jones, T.+13 more
core +1 more source
Pharmacogenomics for personalized pain medicine
Pharmacogenomics aims to unravel the way that human genetic variation affects drug efficacy and toxicity. Genome-wide association studies and candidate gene findings suggest that genetic approaches may help choose the most appropriate drug and dosage while preventing adverse drug reactions (ADRs). Pain is an unpleasant feeling that usually results from
Tai-Ming Ko+6 more
openaire +3 more sources
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda+3 more
wiley +1 more source
Maxillofacial surgery may cause severe complications in perioperative airway management. We report a case of failed airway management in a patient who underwent segmental mandibulectomy, radical neck dissection, and reconstruction with a free flap.
Min A. Kwon+4 more
doaj +1 more source
A Full Transformer-based Framework for Automatic Pain Estimation using Videos [PDF]
The automatic estimation of pain is essential in designing an optimal pain management system offering reliable assessment and reducing the suffering of patients. In this study, we present a novel full transformer-based framework consisting of a Transformer in Transformer (TNT) model and a Transformer leveraging cross-attention and self-attention blocks.
arxiv +1 more source
HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang+11 more
wiley +1 more source
Anesthesia in a Patient with Potocki–Lupski Syndrome
Introduction. Potocki–Lupski syndrome (PTLS) is a rare disease caused by the duplication of a small segment of chromosome 17 (17p11.2). The clinical presentation of this syndrome is quite variable and includes hypotonia, failure to thrive, oropharyngeal ...
Songhyun Kim+4 more
doaj +1 more source
Evidence from web-based dietary search patterns to the role of B12 deficiency in chronic pain [PDF]
Profound vitamin B12 deficiency is a known cause of disease, but the role of low or intermediate levels of B12 in the development of neuropathy and other neuropsychiatric symptoms as well as the relationship of eating meat and B12 levels is unclear.
arxiv +1 more source
Statistical Applications in Pain Management: A Review [PDF]
Chronic pain is a widespread and debilitating condition that affects millions of individuals worldwide. Recent research has unveiled a connection between chronic pain and epigenetic processes, shedding light on the complex interplay between genetics, environment, and pain perception.
arxiv