Results 221 to 230 of about 176,534 (288)

Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo, Dinesh Khanna, Corrado Campochiaro, Vincent Cottin, Fabrizio Luppi, Marco Matucci‐Cerinic, Gianluca Moroncini, Yannick Allanore   +7 more
wiley   +1 more source

Homocitrullinated Peptides Drive Pro‐Inflammatory T Cell Responses in a Humanized Mouse Model of Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Anti‐homocitrullinated protein/peptide antibodies are specific to rheumatoid arthritis (RA) and predictive of worse prognosis, suggesting a pathogenic role for autoreactivity to homocitrullinated peptides (HomoCitP). However, T cell responses to HomoCitP remain largely unexplored.
Sofya Ulanova, Jaspreet Kaur, Gabrielle Buckley, S. M. Mansour Haeryfar, Lisa Cameron, Ewa Cairns, Lillian Barra   +6 more
wiley   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, Accepted Article.
Background Type I interferonopathies are heterogeneous diseases driven by dysregulated IFN‐I signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. Objective To characterize the clinical, immunological, genetic, molecular profiles of patients with suspected enhanced IFN‐I signaling, and assess ...
Ismail Yaz, Seza Ozen, Hacer N. Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet E. Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet O. Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

The role of IgM anti‐acetylated protein antibodies and B cells in the origin of anti‐modified protein autoimmunity in rheumatoid arthritis

Arthritis &Rheumatology, Accepted Article.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated (ACPA), anti‐carbamylated (anti‐CarP), and anti‐acetylated (AAPA) protein antibodies. In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role in early immune responses.
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur HLO, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E.M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

Anterior Cruciate Ligament Reconstruction With Hamstrings Autograft and Modified Lemaire Extra‐articular Tenodesis Using a Single Femoral Tunnel

Arthroscopy Techniques, EarlyView.
Abstract The addition of a lateral extra‐articular procedure to anterior cruciate ligament reconstruction has been shown to improve rotational stability and reduce graft failure rates, particularly in high‐risk patients. However, tunnel convergence remains a major concern in combined anterior cruciate ligament reconstruction and lateral extra‐articular
Alessandro Carrozzo, Valerio Nasso, Silvia Cardarelli, Edoardo Monaco   +3 more
wiley   +1 more source

Single‐Stage Repair of Complex Anterolateral Radial and Posterior Root Tears of the Lateral Meniscus, With a Concomitant Multiligament Knee Reconstruction of the Anterior Cruciate Ligament, Medial Collateral Ligament, Posterior Oblique Ligament, and Anterolateral Ligament in a Young Athlete

Arthroscopy Techniques, EarlyView.
Abstract Early meniscal repair and anatomic reconstruction in a multiligament knee injury optimizes outcomes and restores tibiofemoral mechanics. This technique describes a lateral meniscus posterior root and radial tear repair, with concomitant medial ramp repair, performed during single‐stage reconstruction of the anterior cruciate ligament ...
Romir Patel, Sarah L. Larson, Benjiman J. Wilebski, Luke V. Tollefson, Matthew T. Rasmussen, Dustin R. Lee, Robert F. LaPrade   +6 more
wiley   +1 more source

Open Intrameniscal Examination and Reduction of Depressed Tibial Plateau Fracture

Arthroscopy Techniques, EarlyView.
Abstract In the Schatzker classification, approximately 60.5% of tibial fractures can potentially involve depression fractures of the plateau, on average in types II, III, and IV, and are particularly prevalent among the elderly population. A significant challenge in managing these fractures is achieving optimal visualization of the depressed fracture ...
Sohrab Keyhani, Kamran Shirbache, Iman Menbari Oskouie, Rodrigo Pesantez, Mehdi Komijani, Fardis Vosoughi   +5 more
wiley   +1 more source

Prolotherapy in the Treatment of Knee Osteoarthritis: How to Perform

Arthroscopy Techniques, EarlyView.
Abstract The conservative treatment of knee osteoarthritis is a challenge; since it has no cure, many patients do not want or cannot undergo surgical procedures. Among the various options, we have injectable therapies, especially the so‐called “regenerative,” such as the use of hyaluronic acid, orthobiologicals, and prolotherapy. In the latter, its use
José L. Rocha de Faria, Fabiana Alves C. Menegassi, Sandra T. N. Minamoto, Guilherme Blois V. Pereira, Fábio Henrique P. Videira, Diego G. Severgnine, Caio Gomes de Lima, José Paulo G. Aramburu Filho, Geraldo da R. Motta, João Antônio M. Guimarães, Ronaldo José Faria C. do Amaral, Bianca Gutfilen, Sergio Augusto L. de Souza, Zartur José B. Menegassi   +13 more
wiley   +1 more source