Results 91 to 100 of about 884,774 (339)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Where Have All the Symbols Gone?: A Study of Sufis and Sufi Symbolism in Ottoman Miniature Paintings

open access: yes, 2013
Ottoman miniature paintings represent some of the best preserved and documented works of Islamic art still extant. They differ critically from other forms of miniature painting, such as Persian miniature painting, by not representing Sufi symbolism.
Siegel, Jesse E.
core  

Illuminating Luke: the infancy narrative in Italian Renaissance painting [PDF]

open access: yes, 2005
Title: Illuminating Luke: the infancy narrative in Italian Renaissance painting. Author: Hornik, Heidi J Illuminating Luke 164 p.
Peters, Diane E.
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Strategies for Scaling Businesses in Emerging Markets: Case Study of the Paints and Coatings Industry in Kazakhstan and USA

open access: yesZeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej
This article analyzes how paints and coatings businesses in the USA and Kazakhstan scale between 2019 and 2023. The research employs a non-linear econometric model to identify key factors, including market size, innovation, supply chain efficiency and ...
Andrey Chshelokovskiy
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Studying Form, Color, and Pictorial Composition in the New England Landscape [PDF]

open access: yes, 2017
When I applied for a grant through the Research and Apprenticeship Program (REAP) at the University of New Hampshire (UNH) during the spring of 2016, my intention was to gain more experience in the art of painting outdoors. By looking through the student
Faiella, Daniel
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

The Permanency of Paintings [PDF]

open access: yesThe Journal of Physical Chemistry, 1912
n ...
openaire   +3 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

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