Results 101 to 110 of about 867,900 (301)

Simulated Results of a Passive Energy Retrofit Approach for Traditional Listed Dwellings in the UK

Energies
Energy performance improvements in existing homes play a substantial role in the achievement of the UK’s net-zero emissions target. However, retrofitting dwellings remains a particularly challenging task in the UK, where traditional dwellings make up a ...
Michela Menconi, Noel Painting, Poorang Piroozfar   +2 more
doaj   +1 more source

ABSTRACT PAINTING AS A TRANSFORMATION OF THE COSMOLOGY CONCEPT1 [PDF]

, 2004
Painting in bali in the last three decades has veered towards abstraction.this abstraction is based on narrative and icons,including symbolic and non-symbolic elements, with the use of colour as a major component.
I Wayan , Karja
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Strategies for Scaling Businesses in Emerging Markets: Case Study of the Paints and Coatings Industry in Kazakhstan and USA

Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej
This article analyzes how paints and coatings businesses in the USA and Kazakhstan scale between 2019 and 2023. The research employs a non-linear econometric model to identify key factors, including market size, innovation, supply chain efficiency and ...
Andrey Chshelokovskiy
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Designing and evaluating the efficacy of interactive drawing methods based on parent-child relationship on the symptoms of separation anxiety disorder in 6-8 year old children [PDF]

مجله علوم روانشناختی
Background: Separation anxiety disorder is one of the most common psychological disorders in childhood. Parenting styles and parental anxiety are among the important risk factors that have been identified for the occurrence of separation anxiety disorder.
Nooshin Torabi Goodarzi, Afsaneh Nazeri, Amir Ghamarani   +2 more
doaj  

Reconstructing the image of the ideal city in Renaissance painting and theatre: Its influence in specific urban environments. Digital technology and visual culture [PDF]

, 2016
This paper shows a virtual reconstruction based on a comparative study between scenography designs of urban views, and similar landscapes used in painting, in order to eventually find correspondences with specific urban environments.Universidad de Málaga.
Gonzalez-Roman, Maria del Carmen, Solis-Alcudia, Isabel   +1 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source