Results 101 to 110 of about 189,660 (310)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The role of multiple materials to enrich contemporary mural painting

open access: yesالاكاديمي
The research presents a study on multiple materials and various media in enriching contemporary mural painting in a visual space that allows the formation of a perception enriches the aesthetic vision in the artistic work. Through the diversity of media
Ayad Abdulkareem Mayea   +2 more
doaj   +1 more source

Perceived Crowd Safety in Large Space Buildings: The Confirmatory Factor Analysis of Perceived Risk Variables [PDF]

open access: yesJournal of Engineering, Project, and Production Management, 2018
In crowded large space buildings, safety is one of the most important concerns for facilities managers. Within the built environment, safety has been classified into two main parts: objective safety (normative and substantive) and subjective safety ...
Mohammed Alkhadim   +2 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Painting as Remodel [PDF]

open access: yes, 2019
Yve-Alain Bois’ Painting as Model was first published in 1993 and it still stands as one of the most important collection of essays, looking at painting as both a conceptual and material enquiry.
MICK FINCH   +5 more
core   +2 more sources

From Survival to Self-Expression: Colouring Experiences of Kayayei in Kumasi – Ghana [PDF]

open access: yesE-Journal of Humanities, Arts and Social Sciences
Burial rites are deeply rooted in religious and cultural traditions, shaping how communities understand death, the afterlife, and social belonging. In many rural communities in South Africa, particularly in Shikundu Village, Christian and African burial ...
Dorothy Akpene Amenuke   +1 more
doaj   +1 more source

Inverse Painting: Reconstructing The Painting Process

open access: yesSIGGRAPH Asia 2024 Conference Papers
Project Page: https://inversepainting.github ...
Bowei Chen 0003   +4 more
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Clearing the ground for broad humanity: painting American space [PDF]

open access: yes, 2020
Essay in exhibition catalogue - America : painting a ...
McAuliffe, Chris
core  

Simulated Results of a Passive Energy Retrofit Approach for Traditional Listed Dwellings in the UK

open access: yesEnergies
Energy performance improvements in existing homes play a substantial role in the achievement of the UK’s net-zero emissions target. However, retrofitting dwellings remains a particularly challenging task in the UK, where traditional dwellings make up a ...
Michela Menconi   +2 more
doaj   +1 more source

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