Results 101 to 110 of about 309,898 (310)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Vision of Vincent van Gogh and Maurice Utrillo in Landscape Paintings and their Impact in Establishing the Identity of the Place

open access: yesARCHive-SR, 2017
There are varieties of visions, visual solutions and plastic relations for various painting topics, but the landscape painting is still the closest subject to the identity of the place.
Hala Ibrahim Mohamed Elsaed
doaj   +1 more source

The image of flora and fauna painting in batik craft: Phenomena in ubud, bali

open access: green, 2022
Ni Putu Laras Purnamasari   +3 more
openalex   +1 more source

Characterization of biodegradation in a 17th century easel painting and potential for a biological approach

open access: yesPLoS ONE, 2018
It is important to characterize the microorganisms involved in biodeterioration processes to understand their effects on cultural assets and to define an efficient strategy for protecting artworks, monuments, and buildings from microbiological ...
E. Caselli   +14 more
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

The role of multiple materials to enrich contemporary mural painting

open access: yesالاكاديمي
The research presents a study on multiple materials and various media in enriching contemporary mural painting in a visual space that allows the formation of a perception enriches the aesthetic vision in the artistic work. Through the diversity of media
Ayad Abdulkareem Mayea   +2 more
doaj   +1 more source

Perceived Crowd Safety in Large Space Buildings: The Confirmatory Factor Analysis of Perceived Risk Variables [PDF]

open access: yesJournal of Engineering, Project, and Production Management, 2018
In crowded large space buildings, safety is one of the most important concerns for facilities managers. Within the built environment, safety has been classified into two main parts: objective safety (normative and substantive) and subjective safety ...
Mohammed Alkhadim   +2 more
doaj  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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