Results 121 to 130 of about 884,774 (339)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

Shedding New Light on a Pennsylvania Painter: Finding R. Fibich and His Graveyard

open access: yes, 2012
The painting that would become known as the “York Springs Graveyard” (see cover illustration) was sold to Connecticut folk-art collectors Jean and Howard Lipman in about 1939 by Joe Kindig, an antiques dealer from York, PA.
Pyle, Judith S.
core  

Conceptual painting [PDF]

open access: yes, 2012
Conceptual Painting is an essay that examines if the notion of conceptual painting is a misnomer or if painting is a conceptual approach to art, akin to other mediums.
Bracey, Andrew
core  

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

open access: yesMolecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan   +4 more
wiley   +1 more source

Virtual 3D Reconstruction Hypothesis of the Mural Decorations in the Sala de los Amores, Castulo Archeological Site (Linares, Jaén, Spain)

open access: yesHeritage
The advancement of digital techniques and reduced costs have greatly facilitated their integration into cultural heritage preservation. These technologies are especially valuable in archaeology, where detailed documentation is crucial.
Ana Carrasco-Huertas   +3 more
doaj   +1 more source

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