Results 61 to 70 of about 867,900 (301)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multi-tensor Completion for Estimating Missing Values in Video Data

open access: yes, 2014
Many tensor-based data completion methods aim to solve image and video in-painting problems. But, all methods were only developed for a single dataset.
Cichocki, Andrzej, Guo, Lili, Li, Chao
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Daily stress and everyday annoyances during aging [PDF]

open access: yesСовременная зарубежная психология, 2017
The article regards foreign research on stressors, life events and everyday hardships during aging. The course of events in this period is filled with injuries, sufferings and hard feelings.So the article discusses the existence of a number of factors at
Babakova L.V.
doaj   +1 more source

Waratah theft in Brisbane Water National Park - an analysis of the blue paint poaching reduction program [PDF]

open access: yes, 2010
The flowers of Waratahs, Telopea speciosissima (family Proteaceae) are regularly harvested illegally from natural bushland, particularly close to urban areas such as the New South Wales Central Coast.
Beckers, Doug, Offord, Catherine A.
core  

Estimation of Scribble Placement for Painting Colorization [PDF]

open access: yes, 2013
Image colorization has been a topic of interest since the mid 70’s and several algorithms have been proposed that given a grayscale image and color scribbles (hints) produce a colorized image. Recently, this approach has been introduced in the field of
Rusu, Cristian, Tsaftaris, Sotirios A.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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