Results 71 to 80 of about 472,201 (355)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Does descriptive text change how people look at art? A novel analysis of eye-movements using data-driven Units of Interest

open access: yesJournal of Eye Movement Research, 2017
Does reading a description of an artwork affect how a person subsequently views it? In a controlled study, we show that in most cases, textual description does not influence how people subsequently view paintings, contrary to participants’ self-report ...
Alan Davies   +6 more
doaj   +1 more source

A literature review of analytical techniques for materials characterisation of painted textiles - Part 1: categorising painted textiles, sampling and the use of optical tools [PDF]

open access: yes, 2017
Many types of painted textile are represented in museum collections. Their flexibility, draping qualities, and heterogeneous, layered nature make painted textiles complex objects to conserve. What do we know about their materials and making?
Lennard, Frances   +2 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Documental Survey of Project Prim’art - Portugal Rediscovering Mural Art: Historical and Scientific Study Of Archiepiscopal Évora [PDF]

open access: yes, 2015
The importance of documentary research for art history studies in Cultural Heritage is unquestionable to ascertain the date of a masterpiece, confirmation of authorship and acknowledgement or dismissal of its historical theories.
Araújo, Custódia   +2 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Conservation-restoration Work on the Wall Paintings in the Church of St. George in Lovran

open access: yesZbornik Lovranšćine, 2016
In the sanctuary of the parish church of St. George in Lovran there is a cycle of wall paintings considered to be made around 1470. The wall paintings were discovered in the middle of the 20th century under the layers of colour and plaster from the ...
Kristina Krulić
doaj  

Personal reflections on Jackson Pollock's fractal paintings Reflexões pessoais sobre as pinturas fractais de Jackson Pollock

open access: yesHistória, Ciências, Saúde: Manguinhos, 2006
The art world changed forever when Jackson Pollock picked up a can and poured paint onto a vast canvas rolled across the floor of his windswept barn. Fifty years on, art theorists recognize his patterns as being a revolutionary approach to aesthetics.
Richard Taylor
doaj   +1 more source

Aesthetic judgement of orientation in modern art [PDF]

open access: yes, 2011
When creating an artwork, the artist makes a decision regarding the orientation at which the work is to be hung based on their aesthetic judgement and the message conveyed by the piece.
Mather, George
core   +2 more sources

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