Results 81 to 90 of about 472,201 (355)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

APPLICATION OF TRACE EVIDENCE ANALYSES IN FINE ART IDENTIFICATION TO RULE OUT FRAUDULENT SUBSTITUTION OR DAMAGE

open access: yesТеория и практика судебной экспертизы, 2018
The article examines the utility of trace evidence analysis in facilitating the authentication of works of fine art in the event of their fraudulent substitution, as well as reporting on their overall condition and existing damages.
Shamil’ N. Khaziev, Aleksei V. Bushin
doaj   +1 more source

Paintings of War, Museums of Memory [PDF]

open access: yes, 2017
This paper examines the artists sent to the Western Front under Britain’s official war artists initiative. The government sought to utilize artwork for propagandistic purposes, and to foster emotional connection between civilian and soldier. However, the
Waters, Laura G.
core   +1 more source

A Novel Approach to Artistic Textual Visualization via GAN

open access: yes, 2017
While the visualization of statistical data tends to a mature technology, the visualization of textual data is still in its infancy, especially for the artistic text.
Ma, Muhan, Ma, Yichi
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Between touch and sound.

open access: yesConvergências - Revista de Investigação e Ensino das Artes
This article presents the design of a combined tactile and auditory code for encoding colours for blind individuals, intended for the reproduction of paintings, particularly non-figurative ones.
Manuela Piscitelli
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Cepstral analysis of EEG during visual perception and mental imagery reveals the influence of artistic expertise

open access: yesJournal of Medical Signals and Sensors, 2016
In this article, multichannel electroencephalogram (EEG) signals of artists and nonartists were analyzed during the performances of visual perception and mental imagery of paintings using cepstrum coefficients.
Nasrin Shourie
doaj  

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