Results 141 to 150 of about 100,146 (306)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Ring approximation at equilibrium: The hard sphere pair correlation function
, 2007 Publicación ISIThe ring approximation has been used in the kinetic theory of hard sphere fluids to investigate non-equilibrium phenomena depending on dynamic correlations, not included in the Boltzmann or Enskog equations.
Piasecki, Jaroslaw +1 more
core
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
ANALYSIS OF TWO CLASSES OF CROSS DIFFUSION SYSTEMS [PDF]
, 2010 A mathematical and numerical analysis has been carried out for two cross diffusion systems arising in applied mathematics. The first system appears in modelling the movement of two interacting cell populations whose kinetics are of competition type.
AL-SALMAN, HASSAN,JAWAD
core
Top-quark pair production at high invariant mass: an NNLO soft plus virtual approximation
, 2013 We obtain a soft plus virtual approximation to the NNLO QCD contributions to the top-pair invariant mass distribution at hadron colliders. It is valid up to corrections of order m(t)(2)/M-2, with M the pair invariant mass.
Ferroglia, Andrea +2 more
core +1 more source
Faster Approximate All Pairs Shortest Paths
The all pairs shortest path problem (APSP) is one of the foundational problems in computer science. For weighted dense graphs on $n$ vertices, no truly sub-cubic algorithms exist to compute APSP exactly even for undirected graphs. This is popularly known as the APSP conjecture and has played a prominent role in developing the field of fine-grained ...
Barna Saha, Christopher Ye 0001
openaire +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The pair correlation function in liquid 4He
, 1973 The pair correlation function obtained from the neutron diffraction data of Mozer, De Graaf, and Le Neindre, is given for liquid 4He at several thermodynamic states above and below the superfluid transition.
Mountain, Raymond D.; Raveche, Harold J.
core +1 more source