Results 111 to 120 of about 156,506 (289)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Comparisons of acoustic structures between sexes in a duetting, montane bird

Journal of Avian Biology
Female song in birds is more widespread than previously thought, and studies across different species are critical for better understanding the entire evolutionary process of bird song.
Huan Liu, Fanghong Yang, Qi Zhang, Pengfei Liu, Yuehua Sun   +4 more
doaj   +1 more source

1-Phenyl-3H-2,3-benzodiazepin-4(5H)-one

Acta Crystallographica Section E, 2012
The seven-membered ring in the title compound, C15H12N2O, adopts a boat-shaped conformation (with the methylene C atom as the prow and the double-bond C=N pair of atoms as the stern).
Ballo Daouda, Frédéric Bihel, Mouhamadou Lamine Doumbia, El Mokhtar Essassi, Seik Weng Ng   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Editorial: What's Love Got to Do With It: The Evolution of Monogamy

Frontiers in Ecology and Evolution, 2020
Nancy G. Solomon, Alexander G. Ophir
doaj   +1 more source

4-[(2′-Cyanobiphenyl-4-yl)methyl]morpholin-4-ium nitrate

Acta Crystallographica Section E, 2010
The title ion pair, C18H19N2O+·NO3−, features an N—H...O hydrogen bond linking the cation to the anion. The morpholine portion adopts a chair conformation; the aromatic rings of the biphenylene portion are twisted [torsion ...
Weiwei SiMa
doaj   +1 more source

Determinants and consequences of territory quality in the Bar-throated Apalis Apalis thoracica

, 2011
Includes bibliographical references.The underlying principles of territoriality propose that competition for resources compels individuals to defend areas (territories) that give them exclusive access to critical resources.
Chaskda, Adams Adamanyiwa
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Density Functional Theory (DFT) and Natural Bond Orbital (NBO) Analysis of Intermolecular Hydrogen Bond Interaction in "Phosphorylated Nata De Coco - Water"

Indonesian Journal of Chemistry, 2018
This study aims to study the conformation, the hydrogen bond network, and the stabilities of all the possible intermolecular interactions in phosphorylated nata de coco membrane with water (NDCF-(H2O)n, n = 1-5).
Sitti Rahmawati, Cynthia Linaya Radiman, Muhamad Abdulkadir Martoprawiro   +2 more
doaj   +1 more source