Results 41 to 50 of about 2,114 (237)
Upper paired domination in graphs
AIMS Mathematics, 2021 <abstract><p>A set $ PD\subseteq V(G) $ in a graph $ G $ is a paired dominating set if every vertex $ v\notin PD $ is adjacent to a vertex in $ PD $ and the subgraph induced by $ PD $ contains a perfect matching. A paired dominating set $ PD $ of $ G $ is minimal if there is no proper subset $ PD'\subset PD $ which is a paired dominating ...
Huiqin Jiang +3 more
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Total domination versus paired domination [PDF]
Discussiones Mathematicae Graph Theory, 2012 A dominating set of a graph G is a vertex subset that any vertex of G either belongs to or is adjacent to. A total dominating set is a dominating set whose induced subgraph does not contain isolated vertices. The minimal size of a total dominating set, the total domination number, is denoted by t.
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Audience and Algorithm: A Causal Layered Analysis of the Future of “Autonomy” [PDF]
مطالعات رسانههای نوینExtended AbstractPurpose and Research ProblemIn the digital age, the relationship between audiences and algorithms has become a defining arena of cultural negotiation and epistemic transformation.
Amir Garousi +2 more
doaj +1 more source
Upper bounds on the paired-domination number
Applied Mathematics Letters, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Xue-Gang Chen +2 more
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source