Results 21 to 30 of about 1,898 (218)

Paired-domination in inflated graphs

open access: yesTheoretical Computer Science, 2004
The paper studies inflated graphs of graphs. If \(G\) is a graph, then the inflated graph \(G_I\) of \(G\) is defined. It is obtained from \(G\) by replacing each vertex \(x\) of \(G\) by a clique with the number of vertices equal to the degree of \(x\) in \(G\) and replacing each edge between two vertices by an edge joining vertices of these cliques ...
Kang, L, Sohn, MY, Cheng, TCE
openaire   +4 more sources

Radiation from Collision‐dominated Relativistic Pair Fireballs [PDF]

open access: yesThe Astrophysical Journal, 2001
It is generally accepted that gamma-ray bursts (GRBs) are initiated by a relativistic pair fireball, converting its internal energy into kinetic energy of a relativistically moving plasmoid and subsequently into radiation. Here, we investigate the early stages of this evolution, after the pair fireball has become optically thin to gamma-gamma pair ...
Boettcher, M.   +2 more
openaire   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Graphs with disjoint dominating and paired-dominating sets

open access: yesOpen Mathematics, 2010
Abstract A dominating set of a graph is a set of vertices such that every vertex not in the set is adjacent to a vertex in the set, while a paired-dominating set of a graph is a dominating set such that the subgraph induced by the dominating set contains a perfect matching.
Southey Justin, Henning Michael
openaire   +3 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

The paired-domination and the upper paired-domination numbers of graphs

open access: yesOpuscula Mathematica, 2015
Summary: In this paper we continue the study of paired-domination in graphs. A paired-dominating set, abbreviated PDS, of a graph \(G\) with no isolated vertex is a dominating set of vertices whose induced subgraph has a perfect matching. The paired-domination number of \(G\), denoted by \(\gamma_{p}(G)\), is the minimum cardinality of a PDS of \(G ...
openaire   +1 more source

Paired- and induced paired-domination in (E,net)-free graphs [PDF]

open access: yesDiscussiones Mathematicae Graph Theory, 2012
A dominating set of a graph is a vertex subset that any vertex belongs to or is adjacent to. Among the many well-studied variants of domination are the so-called paired-dominating sets. A paired-dominating set is a dominating set whose induced subgraph has a perfect matching. In this paper, we continue their study.
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

𝐴-stability and dominating pairs [PDF]

open access: yesMathematics of Computation, 1978
It is considered whether linear combinations of A-acceptable exponential approximations preserve the A-stability, when the coefficients of the linear combination are selected in order to achieve exponential fitting. Various pairs of exponential approximations are discussed and the satisfactory pairs are characterized.
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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