Results 211 to 220 of about 198,228 (265)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Hfq-dependent artificial regulatory small RNAs for targeted gene expression control in the nitrogen-fixing <i>Pseudomonas stutzeri</i> A1501. [PDF]

Synth Syst Biotechnol
Han Y, Zhang Y, Li C, Lin M, Lv F, Qi C, Yan Y, Zhan Y.   +7 more
europepmc   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

LICHEN enables light-chain immunoglobulin sequence generation conditioned on the heavy chain and experimental needs. [PDF]

Commun Biol
Capel HL, Ellmen I, Murray CJ, Mignone G, Black M, Clarke B, Breen C, Tierney S, Dougan P, Buick RJ, Greenshields-Watson A, Deane CM.   +11 more
europepmc   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

NUPACK: Computational Nucleic Acid Analysis and Design. [PDF]

ACS Synth Biol
Fornace ME, Huang J, Newman CT, Nanjundiah A, Porubsky NJ, Pierce MB, Pierce NA.   +6 more
europepmc   +1 more source

The functional organization of chromosome territories in single nuclei during zygotic genome activation. [PDF]

Sci Rep
Shankar Ganesh A, Orban TM, Raj R, Fatzinger PI, Johnson A, Riccard SM, Zhanaidarov A, Inaba M, Erceg J.   +8 more
europepmc   +1 more source

Effect of TAR hairpin stabilization on HIV-1 reverse transcription. [PDF]

J Virol
Da Silva Amaral S, Richetta C, Oualid L, Tu NQ, René B, Mauffret O, Delelis O, Fossé P.   +7 more
europepmc   +1 more source

Using wheat-rye 1BL.1RS translocations to disclose the effects of subtelomeric tandem repeats on meiotic behavior of homologues. [PDF]

BMC Plant Biol
Zou Y, Xiong Z, Yang J, Lv H, Guo J, Fu S, Tang Z.   +6 more
europepmc   +1 more source

Possible liquid-nitrogen-temperature superconductivity driven by perpendicular electric field in the single-bilayer film of La₃Ni₂O₇ at ambient pressure. [PDF]

Nat Commun
Shao ZY, Ji JH, Wu C, Yao DX, Yang F.
europepmc   +1 more source