Results 241 to 250 of about 2,161,562 (380)

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Autumn protogyny and spring protandry: Mechanisms and adaptive significance in a Japanese headwater frog, Rana sakuraii. [PDF]

PLoS One
Miwa T.
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Social buffering during fear extinction rescues long-term trauma-induced memory and emotional behavioral alterations in rats. [PDF]

Transl Psychiatry
Blasi E, Di Cesare B, Pisaneschi A, Campolongo P, Morena M.   +4 more
europepmc   +1 more source

A Cytogenetic Survey of a Natural Population of Paeonia japonica, With Special Reference to the Failure of Meiotic Chromosome Pairing

, 1956
Tutomu Haga, T. Ogata
openalex   +2 more sources

Concerning the disconnection of continua by the omission of pairs of their points [PDF]

, 1927
G. T. Whyburn
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

The synaptonemal complex stabilizes meiosis in allotetraploid Brassica napus and autotetraploid Arabidopsis thaliana. [PDF]

New Phytol
Zhang Y, Lv F, Wan Z, Geng M, Chu L, Cai B, Zhuang J, Ge X, Schnittger A, Yang C.   +9 more
europepmc   +1 more source

THE RECIPROCAL SALT-PAIR SYSTEM: SODIUM CHLORIDE – AMMONIUM SULPHITE – SODIUM SULPHITE – AMMONIUM CHLORIDE – WATER AT 20 °C. AND 60 °C.: PART I. TERNARY SYSTEMS [PDF]

, 1955
J. A. Labash, G. R. Lusby
openalex   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source