Results 51 to 60 of about 209,652 (197)

Proton–neutron pairing in N=Z nuclei: Quartetting versus pair condensation

Physics Letters B, 2015
The isoscalar proton–neutron pairing and isovector pairing, including both isovector proton–neutron pairing and like-particle pairing, are treated in a formalism which conserves exactly the particle number and the isospin.
N. Sandulescu, D. Negrea, D. Gambacurta
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Self-pairings on hyperelliptic curves

Journal of Mathematical Cryptology, 2013
A self-pairing is a pairing computation where both inputs are the same group element. Self-pairings are used in some cryptographic schemes and protocols. In this paper, we show how to compute the Tate–Lichtenbaum pairing on a curve more efficiently than
Galbraith Steven D., Zhao Chang-An
doaj   +1 more source

Symmetry restoration in the mean-field description of proton-neutron pairing

Physics Letters B, 2019
We show that the symmetry-restored paired mean-field states (quasiparticle vacua) properly account for isoscalar versus isovector nuclear pairing properties. Full particle-number, spin, and isospin symmetries are restored in a simple SO(8) proton-neutron
A.M. Romero, J. Dobaczewski, A. Pastore
doaj   +1 more source

Paired-end small RNA sequencing reveals a possible overestimation in the isomiR sequence repertoire previously reported from conventional single read data analysis [PDF]

, 2021
José Francisco Sánchez-Herrero, Raquel Pluvinet, Antonio Luna De Haro, Lauro Sumoy   +3 more
openalex   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Exact solution of spherical mean-field plus special orbit-dependent non-separable pairing model with multi non-degenerate j-orbits

Physics Letters B, 2019
Exact solution of spherical mean-field plus a special orbit-dependent non-separable pairing Hamiltonian with multi non-degenerate j-orbits, which is related to two previously known hyperbolic Gaudin models, is explored.
Feng Pan, Dan Zhou, Yingwen He, Siyu Yang, Yunfeng Zhang, J.P. Draayer   +5 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source