Results 31 to 40 of about 138,470 (296)

Anthropometric and micronutrient assessment in pediatric patients with cleft lip and palate in a tertiary care hospital of Haryana, India

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023
Introduction: Cleft lip (CL) and/or cleft palate (CP) are the most common visible craniofacial anomalies throughout the world. CL and CP occur due to a failure of the skeletal components of the mid-face to fuse.
Shikha Sadadiwala, Richa, Shashi Sharma, Antan George, Reena Kumari, Ankush Gaba   +5 more
doaj   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Innocuous presentation of low-grade mucoepidermoid carcinoma of the palate

Journal of Indian Academy of Oral Medicine and Radiology, 2020
Mucoepidermoid carcinoma (MEC) is a malignant epithelial tumor and is the most common minor salivary gland neoplasm. The initial presentation of this pathology can resemble benign lesions and can be misleading.
Thilak T John, Manisha M Khorate, Nivedita Chinam, Poonam R Sawant   +3 more
doaj   +1 more source

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

Six2 Plays an Intrinsic Role in Regulating Proliferation of Mesenchymal Cells in the Developing Palate

Frontiers in Physiology, 2017
Cleft palate is a common congenital abnormality that results from defective secondary palate (SP) formation. The Sine oculis-related homeobox 2 (Six2) gene has been linked to abnormalities of craniofacial and kidney development.
Dennis O. Okello, Paul P. R. Iyyanar, William M. Kulyk, Tara M. Smith, Tara M. Smith, Scott Lozanoff, Shaoping Ji, Shaoping Ji, Adil J. Nazarali   +8 more
doaj   +1 more source

“Intrabony” palatal pleomorphic adenoma: A case report and review of the literature

Sahel Medical Journal, 2021
Pleomorphic adenoma (PA) is the most common neoplasm of the large salivary glands. It derives its name from the architectural pleomorphism seen by light microscopy.
Adekunle Moses Adetayo, Olanike Abosede Oladapo, Modupe Olusola Adetayo   +2 more
doaj   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Tratamiento quirúrgico de insuficiencia velofaringea en pacientes con síndrome velo cardio facial

Anales Médicos, 2023
Introducción: Insuficiencia velofaríngea (IVF) significa que el esfínter velofaríngeo (EVF) no logra sellar la comunicación entre cavidades nasales y tracto vocal situado inferiormente durante el habla.
Pablo-Antonio Ysunza, Matthew Rontal
doaj  

Cleft lip and palate and related factors: A 10 years study in university hospitalised patients at Mashhad - Iran

African Journal of Paediatric Surgery, 2015
Background: Oral-facial clefts including cleft lip and palate are the most common congenital malformations of the head and neck. Environmental factors such as maternal hormonal disorders, use of psychiatric medications, vitamin and folic acid deficiency,
Morteza Noorollahian, Mohsen Nematy, Atiyeh Dolatian, Hengameh Ghesmati, Saeed Akhlaghi, Gholam Reza Khademi   +5 more
doaj   +1 more source

Computational simulation of pacifier deformation and interaction with the palate

Clinical and Experimental Dental Research, 2021
Objectives The objective of this study is to demonstrate that computational finite element models can be used to reliably simulate dynamic interaction between a pacifier, the palate, and the tongue during nonnutritive sucking (NNS).
Christopher L. Lee, Michael Costello, David A. Tesini   +2 more
doaj   +1 more source