Paleovirology of human endogenous retroviruses [PDF]
Retrovirology, 2009 Retroviral infection usually occurs within somatic cells, but occasional infection of germ line cells can lead to integrated retroviral genomes being vertically inherited as host alleles called endogenous retroviruses (ERVs). Once within the host germ line, retroviral genetic material can proliferate via a variety of mechanisms, giving rise to multi ...
Gifford, R +3 more
core +10 more sources
Virus-host co-evolution under a modified nuclear genetic code [PDF]
PeerJ, 2013 Among eukaryotes with modified nuclear genetic codes, viruses are unknown. However, here we provide evidence of an RNA virus that infects a fungal host (Scheffersomyces segobiensis) with a derived nuclear genetic code where CUG codes for serine.
Derek J. Taylor +3 more
doaj +5 more sources
Comparative paleovirological analysis of crustaceans identifies multiple widespread viral groups [PDF]
Mobile DNA, 2015 The discovery of many fragments of viral genomes integrated in the genome of their eukaryotic host (endogenous viral elements; EVEs) has recently opened new avenues to further our understanding of viral evolution and of host-virus interactions. Here, we report the results of a comprehensive screen for EVEs in crustaceans.
Gabriel Metegnier +7 more
core +6 more sources
Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors [PDF]
eLife, 2017 Endogenous retroviral sequences provide a molecular fossil record of ancient infections whose analysis might illuminate mechanisms of viral extinction.
Daniel Blanco-Melo +2 more
doaj +4 more sources
The first endogenous herpesvirus, identified in the tarsier genome, and novel sequences from primate rhadinoviruses and lymphocryptoviruses. [PDF]
PLoS Genetics, 2014 Herpesviridae is a diverse family of large and complex pathogens whose genomes are extremely difficult to sequence. This is particularly true for clinical samples, and if the virus, host, or both genomes are being sequenced for the first time.
Amr Aswad, Aris Katzourakis
doaj +5 more sources
Paleovirology: connecting recent and ancient viral evolution [PDF]
, 2016 Endogenous viral elements, or viral genomic fossils, have proven extremely valuable in the study of the macroevolution of viruses, providing important, and otherwise unobtainable, insights into the ancient origin of viruses, and how their ancestors might have co-evolved with their hosts in the distant past.
Aiewsakun, Pakorn
openaire +4 more sources
Paleovirology of monkeypox virus: Egyptian animal mummies should be in focus. [PDF]
Lancet Microbe, 2022 Saied AA, Metwally AA, Aiash H.
europepmc +3 more sources
Paleovirology and the evolution of virus-host gene exchange [PDF]
, 2016 Paleovirology is the study of viruses at large evolutionary timescales through the investigation of endogenous viral elements (EVEs) that are found in host genomes. EVEs are the result of a heritable, genomic integration of a viral genome in a host germline cell.
Aswad, Amr
openaire +3 more sources
Larger mammalian body size leads to lower retroviral activity [PDF]
, 2014 Retroviruses have been infecting mammals for at least 100 million years, leaving descendants in host genomes known as endogenous retroviruses (ERVs). The abundance of ERVs is partly determined by their mode of replication, but it has also been suggested ...
Belshaw, Robert +5 more
core +22 more sources
Genome-wide identification of Reverse Transcriptase domains of recently inserted endogenous plant pararetrovirus (Caulimoviridae). [PDF]
Front Plant Sci, 2022 Altres ajuts: CERCA Programme/Generalitat de CatalunyaEndogenous viral elements (EVEs) are viral sequences that have been integrated into the nuclear chromosomes. Endogenous pararetrovirus (EPRV) are a class of EVEs derived from DNA viruses of the family
de Tomás C, Vicient CM.
europepmc +3 more sources