Results 91 to 100 of about 22,766 (265)

Epilepsy and systemic autoimmune diseases: A bidirectional two‐sample Mendelian randomization study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epidemiological data indicates that individuals with epilepsy exhibit an elevated susceptibility to autoimmune disorders, and conversely, those with systemic autoimmune diseases (SAD) demonstrate a heightened predisposition to epilepsy.
Ruoshi Tian   +4 more
wiley   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

open access: yesAdvanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

open access: yesIbrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen   +10 more
wiley   +1 more source

Lipid metabolism and inflammation as key drivers in preterm birth: A comprehensive analysis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the alterations in lipid metabolites and circulating inflammatory factors associated with preterm birth, elucidate their interactions, and uncover the underlying pathophysiologic mechanisms. By identifying potential predictive biomarkers and informing the development of effective therapeutic interventions, this ...
Shu Xiao, ChaoChao Wei
wiley   +1 more source

Recent Advances in DNA‐Based Strategies for the Capture, Detection, and Release of Circulating Tumor Cells

open access: yesiLABMED, EarlyView.
Circulating tumor cell (CTC) analysis has become a powerful tool for the early diagnosis of cancer, monitoring disease progression, and evaluating treatment efficacy. This article reviews the latest progress in CTC detection, capture, and release methods based on DNA materials and provides insights into current development trends and future research ...
Lin Zhou, Yongchang Yang, Jie Liu
wiley   +1 more source

Current Progress in Targeting Human Cytomegalovirus Infection

open access: yesiLABMED, EarlyView.
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley   +1 more source

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