Palindromic onset of rheumatoid arthritis. Clinical, synovial fluid, and biopsy studies [PDF]
, 1982 H. Ralph Schumacher
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ChemistryEurope, EarlyView.Larger‐scale enzymatic synthesis of base‐modified DNA is developed using primer extension with KOD(exo‐) DNA polymerase allowing preparation of milligram amounts of the modified DNA sufficient for NMR structural analysis. Milligram (≈200 nmol) scale enzymatic synthesis of base‐modified DNA is developed based on primer extension using easily accessible ...
Veronika Raindlová +6 more
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Molecular organization ofsbcC, a gene that affects genetic recombination and the viability of DNA palindromes inEscherichia coliK-12 [PDF]
, 1989 Isam Naom +3 more
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Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics
Clinical Pharmacology &Therapeutics, EarlyView.The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou +6 more
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Structure and function of an AT-rich, interspersed repetitive sequence fromChironomus thummi: solenoidal DNA, 142 bp palindrome-frame and homologies with the sequence for site-specific recombination of bacterial transposons [PDF]
, 1983 Norbert Israelewski
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ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu +9 more
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Epilepsy and systemic autoimmune diseases: A bidirectional two‐sample Mendelian randomization study
Epilepsia Open, EarlyView.Abstract Objective Epidemiological data indicates that individuals with epilepsy exhibit an elevated susceptibility to autoimmune disorders, and conversely, those with systemic autoimmune diseases (SAD) demonstrate a heightened predisposition to epilepsy.
Ruoshi Tian +4 more
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Advanced Genetics, Volume 6, Issue 1, March 2025.This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
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Delving Into the Dialogue between Epigenetic Modifications and Immunometabolism in Cancer
Advanced Genetics, EarlyView.Epigenetic modifications—including DNA, histone, and RNA modifications—and their interplay play pivotal roles in tumorigenesis and progression. The crosstalk between tumor immunometabolism and epigenetic regulation has garnered significant attention, as metabolites serve as epigenetic modulators to modulate immune cell activation, differentiation, and ...
Xiaowen Xie +5 more
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The effects of trinucleotide repeats found in human inherited disorders on palindrome inviability in Escherichia coli suggest hairpin folding preferences in vivo. [PDF]
, 1995 John M. Darlow, David R. F. Leach
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