Results 191 to 200 of about 22,958 (312)

Interleukin‐1 receptor type II and inflammatory bowel disease: A Mendelian randomization study

Rheumatology &Autoimmunity, EarlyView.
This Mendelian Randomization study investigated the association between interleukin‐1 receptor type II (IL‐1RII) and inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC) by utilizing the genome‐wide association studies summary statistics.
Qifan Feng, Nan Li, Yawen Lu, Yinqi Long, Yaru Zhang, Kexin Ma, Shengxiao Zhang, Caihong Wang   +7 more
wiley   +1 more source

Different management methods for tunnel abscess in tunneled cuffed catheters with catheter-related bloodstream infections and central venous stenosis: two case reports. [PDF]

BMC Nephrol
Bai Y, Wang C, Xu M, Li H, An N, Chen R.
europepmc   +1 more source

Binding of the metalloregulatory protein DtxR to the diphtheria tox operator requires a divalent heavy metal ion and protects the palindromic sequence from DNase I digestion.

, 1992
Xueqin Tao, John R. Murphy
openalex   +1 more source

Update on Gene Therapy in the Treatment of Hereditary Hearing Loss

Sensory Neuroscience, EarlyView.
Gene therapy is a promising therapeutic approach for genetic disorders, including three major gene therapy strategies: gene replacement, gene suppression, and gene editing. After transmitting genes to the inner ear through appropriate pathways, repair the cochlea in order to achieve the goal of treating hereditary hearing loss.
Weiwei He, Shanying Han, Xinghong Liu, Xiaotong Huang, Wen Yang, Xinghua Tang, Chuan Dong, Jiangang Fan   +7 more
wiley   +1 more source

Inter-chromosomal insertions at Xq27.1 associated with retinal dystrophy induce dysregulation of LINC00632 and CDR1as/ciRS-7. [PDF]

Am J Hum Genet
Gardner JC, Jovanovic K, Ottaviani D, Melo US, Jackson J, Guarascio R, Ziaka K, Hau KL, Lane A, Taylor RL, Chai N, Gkertsou C, Fernando O, Piwecka M, Georgiou M, Mundlos S, Black GC, Moore AT, Michaelides M, Cheetham ME, Hardcastle AJ.   +20 more
europepmc   +1 more source

Transcriptional enhancer activity of hr5 requires dual-palindrome half sites that mediate binding of a dimeric form of the baculovirus transregulator IE1

, 1995
Steven Rodems, Paul D. Friesen
openalex   +1 more source

A unique junctional palindromic sequence in mitochondrial DNA from a patient with progressive external ophthalmoplegia [PDF]

, 2000
Takuya Saiwaki
openalex   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Quorum Sensing in <i>Chromobacterium subtsugae</i> ATCC 31532 (Formerly <i>Chromobacterium violaceum</i> ATCC 31532): Transcriptomic and Genomic Analyses. [PDF]

Microorganisms
Deryabin DG, Inchagova KS, Nikonorova ER, Karimov IF, Duskaev GK.   +4 more
europepmc   +1 more source

Palindromes as Substrates for Multiple Pathways of Recombination in Escherichia coli [PDF]

, 2000
Gareth A. Cromie, Catherine B. Millar, Kristina Schmidt, David R. F. Leach   +3 more
openalex   +1 more source