Results 11 to 20 of about 45,603 (283)

CRISPR genome editing using computational approaches: A survey

open access: yesFrontiers in Bioinformatics, 2023
Clustered regularly interspaced short palindromic repeats (CRISPR)-based gene editing has been widely used in various cell types and organisms. To make genome editing with Clustered regularly interspaced short palindromic repeats far more precise and ...
Roghayyeh Alipanahi   +2 more
doaj   +1 more source

The complete chloroplast genome of Diplodiscus trichospermus and phylogenetic position of Brownlowioideae within Malvaceae

open access: yesBMC Genomics, 2023
Background Malvaceae is an economically important plant family of 4,225 species in nine subfamilies. Phylogenetic relationships among the nine subfamilies have always been controversial, especially for Brownlowioideae, whose phylogenetic position remains
Mingsong Wu   +5 more
doaj   +1 more source

Rare immune diseases paving the road for genome editing-based precision medicine

open access: yesFrontiers in Genome Editing, 2023
Clustered regularly interspaced short palindromic repeats (CRISPR) genome editing platform heralds a new era of gene therapy. Innovative treatments for life-threatening monogenic diseases of the blood and immune system are transitioning from semi-random ...
Mara Pavel-Dinu   +3 more
doaj   +1 more source

An intriguing shift occurs in the novel protein phosphatase 1 binding partner, TCTEX1D4: evidence of positive selection in a pika model. [PDF]

open access: yesPLoS ONE, 2013
T-complex testis expressed protein 1 domain containing 4 (TCTEX1D4) contains the canonical phosphoprotein phosphatase 1 (PPP1) binding motif, composed by the amino acid sequence RVSF.
Luís Korrodi-Gregório   +9 more
doaj   +1 more source

X-linked palindromic gene families 4930567H17Rik and Mageb5 are dispensable for male mouse fertility

open access: yesScientific Reports, 2022
Mammalian sex chromosomes are enriched for large, nearly-identical, palindromic sequences harboring genes expressed predominately in testicular germ cells.
Evan R. Stark-Dykema   +3 more
doaj   +1 more source

Cutting sequences and palindromes [PDF]

open access: yes, 2010
We give a unified geometric approach to some theorems about primitive elements and palindromes in free groups of rank 2. The geometric treatment gives new proofs of the theorems. Dedicated to Bill Harvey on his 65th birthday.
Jane Gilman, Linda Keen
openaire   +3 more sources

Highly efficient site-specific integration of DNA fragments into the honeybee genome using CRISPR/Cas9

open access: yesG3: Genes, Genomes, Genetics, 2022
Functional genetic studies in honeybees have been limited to transposon mediated transformation and site directed mutagenesis tools. However, site- and sequence-specific manipulations that insert DNA fragments or replace sequences at specific target ...
Anna Wagner, Jana Seiler, Martin Beye
doaj   +1 more source

ON "VERY PALINDROMIC" SEQUENCES [PDF]

open access: yesJournal of the Korean Mathematical Society, 2015
We consider the problem of characterizing the palindromic sequences 〈cd−1, cd−2, . . . , c0〉, cd−1 6= 0, having the property that for any K ∈ N there exists a number that is a palindrome simultaneously in K different bases, with 〈cd−1, cd−2, . . . , c0〉 being its digit sequence in one of those bases.
openaire   +3 more sources

The mitochondrial and plastid genomes of Volvox carteri: bloated molecules rich in repetitive DNA

open access: yesBMC Genomics, 2009
Background The magnitude of noncoding DNA in organelle genomes can vary significantly; it is argued that much of this variation is attributable to the dissemination of selfish DNA.
Lee Robert W, Smith David
doaj   +1 more source

String attractors of Rote sequences [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science
In this paper, we describe minimal string attractors (of size two) of pseudopalindromic prefixes of standard complementary-symmetric Rote sequences. Such a class of Rote sequences forms a subclass of binary generalized pseudostandard sequences, i.e., of ...
Lubomíra Dvořáková   +1 more
doaj   +1 more source

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